Guides
Clear, practical answers for people considering a clinical trial.
Recently added guides
- Why diversity in clinical trials matters · 6 min read
- Tuskegee and the safeguards that exist now · 7 min read
- Your rights as a clinical trial participant · 5 min read
- A caregiver's guide to clinical trials · 7 min read
All guides
How to join a clinical trial
A step-by-step guide to finding a trial, contacting the study team, screening and informed consent.
6 min read
Understanding clinical trial phases
What Phase 1, 2, 3 and 4 trials mean, and what each phase is designed to learn.
4 min read
Questions to ask before joining a trial
A practical checklist of questions to ask the research team before you decide to take part.
3 min read
What is informed consent?
What informed consent means in a clinical trial, what the consent form covers, your rights, and how you can withdraw at any time.
6 min read
Do clinical trials pay? Compensation explained
How clinical trial payments work: stipends, travel reimbursement, what's typical, what affects the amount, and what to ask the study team.
6 min read
Are clinical trials safe? Risks and benefits
How clinical trials are overseen, what risks to expect, how your safety is monitored, and how to weigh risks against possible benefits.
7 min read
Placebos in clinical trials: what it means for you
What a placebo is, when trials use one, whether you'll know what you're getting, and how standard-of-care comparisons work.
5 min read
How long do clinical trials take?
How long clinical trials last by phase, the difference between your time commitment and the overall study length, and what affects the timeline.
5 min read
What happens at a clinical trial screening visit?
What to bring to a clinical trial screening visit, the tests involved, how long it takes and common reasons people don't qualify.
6 min read
Why was I excluded from a clinical trial?
Common reasons people are excluded from clinical trials, what it means, and what to do next — including finding other trials.
5 min read
How to talk to your doctor about clinical trials
When to bring up clinical trials with your doctor, what to ask, how to get a referral and how to prepare for the conversation.
5 min read
Decentralized and virtual clinical trials explained
What decentralized and virtual clinical trials are, how remote visits work, and the pros and cons of taking part from home.
5 min read
Randomization in clinical trials: how it works
What randomization means in a clinical trial, why it matters for fair results, and how blinding works — explained simply.
5 min read
Why diversity in clinical trials matters
Why some groups are under-represented in clinical trials, why it matters for how well treatments work for everyone, and what is changing.
6 min read
Tuskegee and the safeguards that exist now
The honest history of the Tuskegee syphilis study, and the protections it led to: ethics review, informed consent and your right to leave.
7 min read
Your rights as a clinical trial participant
Your rights in a clinical trial: voluntary participation, leaving at any time, getting answers to your questions, and how your privacy is protected.
5 min read
A caregiver's guide to clinical trials
Searching for a trial for a spouse, parent or child? How to search on their behalf, what consent means, and how to look after yourself too.
7 min read
What to say when you call a clinical trial site
A practical call script: what to have ready, exactly what to say first, the key questions to ask, and what to do if the answer is no.
6 min read
Your clinical trial journey: a step-by-step checklist
The whole path from finding a trial to leaving one, as a checklist: eligibility, your doctor, first contact, screening, consent and taking part.
6 min read