Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 18 Years and older
- Sex
- All sexes
- Healthy volunteers
- Accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
- Procedures mentioned: Ultrasound
Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.
Show the study's own words
- "Combining the advantages of both light and ultrasound scanning, PAT holds promise to present objective optical information in subsurface joint tissues with high sensitivity and high spatial resolution."
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
In plain language
This study tests whether a new laser-based imaging tool called photoacoustic tomography (PAT) can detect long-term rheumatoid arthritis, a disease that causes swollen, painful joints. It is for adults with a history of rheumatoid arthritis.
The purpose of this feasibility study is to determine if a new emerging technology called photoacoustic tomography (PAT) can be adapted for use in humans for the detection of chronic rheumatoid arthritis.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Who can join
- Men and women age 18 or older.
- Have had rheumatoid arthritis for more than 2 years and have a referral from your arthritis doctor.
- The study also lists healthy volunteers with a known history of rheumatoid arthritis as eligible.
Who can't join
- Have an implant activated by electricity, magnets, or movement, such as a pacemaker, magnetic surgical clip, artificial body part, or implanted nerve stimulator.
- Are pregnant.
- Have a fear of tight or closed spaces.
- Have kidneys that do not work well, or receive dialysis, a treatment that filters your blood.
- Have shock with low blood pressure, or unstable low blood pressure.
- Have rhabdomyolysis, a condition in which muscle tissue breaks down.
- Had an MRI or MRA scan with gadolinium contrast in the past 3 months. This contrast is injected into a vein to make images clearer.
Simplified for readability. The official criteria below are what the study team uses.
Official eligibility criteria
Inclusion Criteria: * Men and women 18 years of age or older can participate in this study. * Patients can participate in this study if they have had rheumatoid arthritis for more than 2 years and their rheumatologist has referred them to this study. * Patients can participate as a healthy volunteer with a known history of rheumatoid arthritis. Exclusion Criteria: * Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator. * Pregnant patients. * Patients who is claustrophobic. * Patients with impaired renal function cannot participate in this study such as elevate creatinine clearance, patients on kidney dialysis etc. * Patients with shock hypotension or unstable low blood pressure. * Patients with Rhabdomyolysis. * Patients who have had a contrast enhanced (with gadolinium) MRA (magnetic resonance angiography)/ or MRI within the last 3 months. (Contrast is a medication injected into a vein during a imaging examination that helps produce clearer images/pictures).
Study sites (1)
MI
- Universtity of Michigan Health System · Ann Arbor, MI 48109Xueding Wang, PHD · Principal investigatorMore trials in Ann Arbor