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Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years and older
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Mentioned in the study description

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Time periods mentioned: 1 year
  • Procedures mentioned: Questionnaires, X-rays, CT scans, MRI scans

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "This is a questionnaire-based study."
  • "Stereotactic radiosurgery (SRS) is a treatment that uses high-energy highly-focused radiation (X-rays) to destroy a tiny region in the brain that causes tremor to occur."
  • "This clinical trial is a questionnaire-based trial that only involves completion of 2 questionnaires at the consultation appointments with neurology and radiation oncology."
  • "The questionnaires only take a few minutes and will provide us with valuable information about how severe the patient's tremor is before and after SRS treatment at 3-month intervals for 1 year."
  • "For clinical trial participation, a questionnaire will be completed as a baseline measurement (this takes a few minutes)."
  • "For clinical trial participation, a questionnaire will be completed as a baseline assessment of the patient's tremor-related quality of life (this takes a few minutes). 5."
Compensation
Mentioned in the study description
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study looks at changes in shaking (tremor) and quality of life after stereotactic radiosurgery (SRS), a focused radiation treatment. It uses questionnaires and is for adults with essential tremor or Parkinsonian tremor that medicine does not control well enough.

The purpose of this study is to determine the changes in quality of life and degree of tremor for patients with essential tremor or Parkinsonian tremor who are treated by stereotactic radiosurgery (SRS). This is a questionnaire-based study. Please see Detailed Description below for more information.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • A neurologist (a doctor who treats brain and nerve problems) must confirm essential tremor or Parkinsonian tremor that medicine does not control well enough.
  • Prefer radiation treatment over surgery to place a deep brain stimulation (DBS) device or destroy a small part of the brain involved in tremor.
  • Be at least 18 years old.

Who can't join

  • Have a medical reason you cannot receive radiation to the head, such as past radiation to the thalamus (a part of the brain).
  • Cannot have an MRI scan of the brain.
  • Have had a surgical thalamotomy (surgery to destroy a small part of the brain involved in tremor). A deep brain stimulation (DBS) device on the opposite side is allowed.
  • Are expected to live less than 1 year.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Must be certified by a neurologist as having essential tremor or Parkinsonian tremor that is insufficiently controlled by medication alone. * Preference to receive radiation treatment for tremor treatment, rather than surgical DBS implantation or surgical thalamotomy * At least 18 years old Exclusion Criteria: * Contraindications to cranial radiation (such as prior radiation to the thalamus) * Inability to have a MRI of the brain * Prior surgical thalamotomy treatment (but contralateral deep brain stimulator \[DBS\] is permitted) * Estimated life expectancy less than 1 year

Study sites (1)

TN