RightFit
RecruitingPhase not listed

Rheumatoid Arthritis Patients at Risk for Interstitial Lung Disease

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
45 Years to 90 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study looks at early lung disease in people with rheumatoid arthritis (RA), a disease that causes joint swelling and pain. It aims to find signs that predict whether lung changes will worsen on scans, even before symptoms appear. The study is for adults ages 45 to 90 with RA.

The overall goal of this study is to define the phenotype of Interstitial Lung Disease (ILD), and identify factors that predict radiologic progression in those with subclinical RA-ILD, in patients with rheumatoid arthritis (RA). The investigators hypothesize that there are common core elements (e.g. clinical features, genetic variants, and/or biologic markers) between other forms of ILD (e.g. idiopathic pulmonary fibrosis, IPF) and subclinical RA-ILD that places individuals at risk for the development of lung disease.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Age 45 or older.
  • Have RA diagnosed using the 2010 American College of Rheumatology rules.

Who can't join

  • Cannot give informed consent, meaning you cannot understand and agree to join the study.
  • Are pregnant.
  • Have a history of interstitial lung disease, which affects tissue around the lungs’ air sacs.
  • Have signs of widespread lung tissue disease from another cause, such as infection, harm from a drug, or another disease where the immune system attacks the body.
  • Are older than 90 or younger than 45.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: 1. ≥ 45years old 2. Diagnosis of RA using the 2010 American College of Rheumatology (ACR) criteria Exclusion Criteria: 1. Inability to give informed consent 2. Pregnant women 3. History of interstitial lung disease 4. Evidence of other causes of diffuse parenchymal lung disease such as infection, drug toxicity, other autoimmune processes, etc. 5. Subjects over the age of 90 years old or less than 45 years old

Study sites (1)

CO