Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer
Measuring the Effectiveness of a Continuous Positive Airway Pressure (CPAP) Device to Reduce Tumor Motion and Increase Lung Volume Expansion in Patients Undergoing Stereotactic Body Radiotherapy (SBRT) for Tumors That Move With Respiration
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 18 Years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
Not stated in the study description — ask the study team about visits and procedures.
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
In plain language
This study tests two ways to reduce lung tumor movement during stereotactic body radiation therapy (SBRT), a focused radiation treatment for lung cancer. It compares a CPAP device, which blows air into the lungs through a mask or nozzle, with taking a deep breath and holding it. The study is for people who will receive SBRT at MD Anderson.
This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowing air into the lungs while patients wear a face mask or nozzle to help expand their airways and lungs. Deep inspiration breath hold is a standard technique that uses active breath-holding to restrict movement of the body. Using a continuous positive airway pressure device may work better than deep inspiration breath hold in lowering the amount of tumor movement during stereotactic radiation body therapy.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Who can join
- You will receive SBRT through the Thoracic Radiation Oncology Service at MD Anderson.
Who can't join
- You have a medical reason that makes using a CPAP device unsafe.
- You have not signed the study's informed consent form, which explains the study and asks for your agreement to join.
- You are unable or unwilling to cooperate.
- You are not fully awake or aware.
- You have had an injury or burns to your face.
- You have had surgery on your face, food pipe, stomach, or sinuses in the past 3 months.
- Your medical history shows idiopathic pulmonary fibrosis (IPF), lung scarring with no known cause.
- You are an adult unable to consent, are not yet an adult, are pregnant, or are a prisoner.
Simplified for readability. The official criteria below are what the study team uses.
Official eligibility criteria
Inclusion Criteria: * The patient will receive stereotactic body radiotherapy in the Thoracic Radiation Oncolcogy Service at MD Anderson. Exclusion Criteria: * The patient has a contra-indication for using a CPAP device. * The patient has not signed a study-specific informed consent for this study. * The patient is uncooperative. * The patient has reduced consciousness. * The patient has sustained trauma or burns to the face. * The patient has undergone any facial, esophageal, gastric or sinus surgery within the last 3 months. * The patient has idiopathic pulmonary fibrosis (IPF) as documented in their medical history. * Adults who are unable to consent, individuals who are not yet adults, pregnant women and prisoners will be excluded from this study.
Study sites (1)
TX
- M D Anderson Cancer Center · Houston, TX 77030Julianne M. Pollard, MD · Study contact · 713-563-2591Julianne M. Pollard, MD · Principal investigatorMore trials in Houston