RightFit
RecruitingNot applicable

Brown Adipose Tissue Activation by Spinal Cord Stimulation

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
21 Years to 70 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests whether spinal cord stimulation, which uses electrical signals, can increase how much energy body fat burns. It aims to help with weight loss and possibly type 2 diabetes. It is for adults ages 21–70 with ongoing nerve pain in their legs and back who already plan to get this treatment for pain.

The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Are 21–70 years old.
  • Have ongoing nerve pain in your legs and back.
  • Already plan to get spinal cord stimulation for pain.
  • Have not had a test run of spinal cord stimulation for pain.
  • Have a body mass index (BMI) of 25–45. BMI is a measure based on height and weight.

Who can't join

  • Are not considering spinal cord stimulation for pain.
  • Are a forensic patient (a patient involved with the legal system).
  • Take beta blockers, a type of medicine.
  • Had a weight change of more than 5% in the last 3 months.
  • Regularly use tobacco or regularly drink too much alcohol.
  • Are pregnant.
  • Are an adult who cannot make informed decisions, or are a child or newborn.
  • Have a BMI below 25 or above 45.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: 1. Age: 21-70 years 2. Persistent neuropathic leg and back pain 3. Subjects who are already planning to undergo SCS for pain 4. Subjects who have not received a prior SCS trial for pain 5. Subjects with a BMI of 25-45, using formula; weight (lb) / \[height (in)\]2 x 703 Exclusion Criteria: 1. Not considering SCS for pain 2. Forensic patient 3. Taking beta blockers 4. Weight change \> 5% within last 3 months 5. Habitual tobacco use 6. Habitual excessive alcohol use 7. Pregnancy 8. Decisionally impaired adults 9. Children 10. Neonates 11. Subjects with a BMI of \<25 or \>45

Study sites (1)

OR