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RecruitingEarly Phase 1

Entire-body PET Scans for Multiple Sclerosis

Exploratory Study of Entire-body PET Scans for Multiple Sclerosis

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
25 Years to 55 Years
Sex
All sexes
Healthy volunteers
Accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests whether whole-body PET scans can better measure and track damage to the protective covering around nerves in people with multiple sclerosis (MS). It includes people with MS and healthy volunteers.

To evaluate whether an entire-body positron emission tomography (PET) scanner can be exploited to improve evaluation, monitoring and measurement of both peripheral and central demyelination in multiple sclerosis (MS) patients.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Have MS diagnosed by a qualified nerve and brain doctor with experience treating MS, or be a healthy volunteer.
  • Be willing and able to lie still on the PET-CT scan bed for 10 to 20 minutes.

Who can't join

  • Have another illness that could complicate MS, including a brain, nerve, or mental health condition unrelated to MS that was diagnosed before MS symptoms began.
  • Are pregnant or breastfeeding.
  • Have diabetes or another disorder affecting hormones or how the body uses energy.
  • Have a known current short-term infection.
  • Have a history of cancer that spread to nearby tissue or other parts of the body.
  • Recently had surgery, chemotherapy, or radiation treatment.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Multiple sclerosis (MS) patients diagnosed by a credentialed neurologist experienced with care of multiple sclerosis patients. * Normal healthy subjects. * Willing and able to lie motionless on the PET-CT scanner bed for at least 10 minutes and up to 20 minutes for the duration of the PET-CT medical imaging scan. Exclusion Criteria: * Any additional complicating medical illness other than MS including any other neuropsychiatric illness unrelated to MS diagnosed prior to the onset of initial symptoms of MS. * Pregnancy or breast feeding. * Diabetes or other metabolic-endocrine disorders. * Any known concomitant acute infection. * History of metastatic or locally invasive cancer. * Recent surgery, chemotherapy or radiation therapy.

Study sites (1)

CA