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Understanding Motivation in Parkinson's Patients Through Neurophysiology

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years and older
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Procedures mentioned: Wearing a device

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "Additionally, participants will wear a device that captures movement, sleep, heart rate variability, and self-reported measures."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study looks at how deep brain stimulation (DBS) affects motivation and choices about effort, rewards, and timing. People with Parkinson’s disease or dystonia who have an implanted DBS device will do tasks while the device records brain signals.

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Has Parkinson’s disease or dystonia, a condition that causes muscles to tighten without control.
  • Has a Medtronic Percept or RC+S DBS device, which sends electrical signals to the brain.
  • The device is placed in a brain area called the GPi or STN, on one or both sides of the brain.
  • Male or female.
  • Had DBS surgery more than 1 month ago.

Who can't join

  • Has severe problems with thinking or memory.
  • Scores below 20 on the MoCA, a test of thinking and memory.
  • Is pregnant.
  • Is younger than 18.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Has Parkinson's Disease or Dystonia * Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN * Has DBS device implanted either bilaterally or unilaterally * Male or female * More than 1 month post-DBS surgery Exclusion Criteria: * Severe cognitive impairments * Has MOCA score below 20 * Pregnancy * Age less than 18 years old

Study sites (1)

CA