Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 30 Weeks to 83 Months
- Sex
- All sexes
- Healthy volunteers
- Not accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
Not stated in the study description — ask the study team about visits and procedures.
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
In plain language
This study looks at whether breathing patterns in the newborn intensive care unit (NICU) are linked to later asthma, breathing problems during sleep, or problems with learning and development. It is for children under age 7 who were born before 29 weeks of pregnancy and took part in the Pre-Vent study.
Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic measures are lacking. This study wants to learn if these problems are related to certain patterns of breathing that babies had while they were in the NICU.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Who can join
- Took part in a Pre-Vent study with signed consent or permission to contact the family about future research.
- Born before 29 weeks of pregnancy.
- Under age 7 when joining this study.
Who can't join
- Left the Pre-Vent study after consent was signed, for any reason.
- Had no data on body functions recorded during Pre-Vent.
- The local research review board or Department of Children and Family Services has not approved contacting the family again.
- Was adopted by a family that does not give consent.
- A parent had already refused further contact before being approached for this study.
- Joined Pre-Vent at Washington University in St. Louis, which is not taking part in this study.
Simplified for readability. The official criteria below are what the study team uses.
Official eligibility criteria
Inclusion Criteria: * Enrolled in any Institutional Review Board (IRB) protocol of the Pre-Vent Study that had signed consent, or in any IRB protocol of the Pre-Vent Study that authorized re-contact for future research * Born \<29 weeks gestational age * Age at enrollment less than 7 years old Exclusion Criteria: * Subject was withdrawn from the Pre-Vent study after signing Pre-Vent consent form, for any reason * Subject had no physiological data recorded as part of Pre-Vent * Lack of regulatory approval from local IRB or Department of Children and Family Services (DCFS) to recontact subjects * Adopted by non-consenting family * Parent refused further contact, prior to approach for Post-Vent * Infant enrolled in Pre-Vent at Washington University St Louis, which is not a Post-Vent participating site.
Study sites (1)
IL
- Ann & Robert H. Lurie Children's Hospital of Chicago · Chicago, IL 60611Erin Lonergan, RRT, MS · Study contactCasey Rand · Study contactMore trials in Chicago