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Tennessee Alzheimer's Project

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
60 Years and older
Sex
All sexes
Healthy volunteers
Accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

The Tennessee Alzheimer's Project gathers health information to help researchers find ways to detect, prevent, and treat Alzheimer's disease. It is for adults age 60 or older with no memory or thinking problems, mild problems, or Alzheimer's disease. Participants have yearly study visits and are referred to other research studies.

The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both local and national investigator studies to develop early detection, prevention, and treatment strategies for Alzheimer's disease. The Clinical Core intends to enroll up to 1000 participants, including individuals who are cognitively unimpaired, have mild cognitive impairment, or have Alzheimer's disease. This cohort of about 1000 participants will be called the Tennessee Alzheimer's Project. Participants will be seen annually for comprehensive clinical characterization and then referred to other studies to enhance Alzheimer's disease research activities.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Be age 60 or older.
  • Meet standard guidelines for having no memory or thinking problems, mild problems, or Alzheimer's disease.
  • Speak English.
  • Be able to understand and decide whether to join the study when it starts.

Who can't join

  • Have no reliable study partner who interacts with you often and can join visits in person or by phone.
  • Have a history of a major mental illness, such as schizophrenia or bipolar disorder.
  • Have a history of a brain or nerve illness, such as epilepsy, multiple sclerosis, or Parkinson's disease.
  • Have had a head injury that caused a major loss of consciousness.
  • Cannot have an MRI scan, which uses magnets to take pictures inside the body. Reasons may include fear of small spaces or iron-containing metal in your body.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Age 60 or older * Meet standard criteria for (a) cognitively unimpaired, (b) mild cognitive impairment, or (c) Alzheimer's disease * English speaking * Individuals who lack decisional capacity to provide informed consent at baseline will not be enrolled in the study Exclusion Criteria: * No available reliable study partner (reliable is defined as someone who interacts significantly with the participant and is available to participate in study visits in person or by phone) * History of major psychiatric illness (e.g., schizophrenia, bipolar), neurological illness (e.g., epilepsy, multiple sclerosis, Parkinson's disease), or head injury with significant loss of consciousness. * Unable to undergo MRI (e.g., claustrophobia, ferrous metal in body)

Study sites (1)

TN