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Depression and Driving

The Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older Adults (Depression and Driving)

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
65 Years and older
Sex
All sexes
Healthy volunteers
Not stated
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study looks at how depression, early signs of Alzheimer's disease before symptoms appear, and medicines for depression affect driving. It is for adults age 65 or older who have normal memory and thinking skills.

This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Drive at least once a week on average.
  • Have a valid driver's license.
  • Be willing to have blood drawn.
  • Be willing to have either a spinal tap (a test that takes fluid from the lower back) or a PET scan (an imaging test).
  • Be age 65 or older.
  • Speak English.

Who can't join

  • Not willing to have blood drawn or to have one other test for signs of disease.
  • Be younger than 65.
  • Do not drive or are no longer actively driving.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Drive on average at least once per week * Has a valid driver's license * Willing to complete blood draw * Willing to complete either lumbar puncture or PET imaging * 65 years or older * Speaks English Exclusion Criteria: * Not willing to complete blood draw and/or one other biomarker * Less than 65 years of age * Does not drive a vehicle/ is no longer actively driving

Study sites (1)

MO