RightFit
RecruitingNot applicable

Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
40 Years to 75 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests computer-based brain exercises and Tai Chi–Qi Gong training for people with early-onset Alzheimer's disease. It will compare these activities with a different training program to see if they improve thinking, daily tasks, and mood.

The purpose of this study is to generate preliminary data on the benefit of computerized cognitive training and Tai Chi- Qi Gong training in participants with Early-Onset Alzheimer's Disease. It is hypothesized that participants in the experimental training condition will perform better on outcomes related to cognition, functioning, and mood at follow-up compared to participants assigned to the active control condition.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Be enrolled in the LEADS study and diagnosed by that study with early-onset Alzheimer's disease with amyloid, a protein linked to Alzheimer's.
  • Have been 40 to 64 years old when joining LEADS.
  • Speak English fluently.
  • Be in good general health, with no other brain or nerve disorder.
  • Have someone who knows you well and can share information about you.
  • Have had a Clinical Dementia Rating score of 0.5 to 1.0 when joining LEADS. This scale measures how much dementia affects daily life.
  • Be able to see, hear, understand instructions, and use your hands well enough to do the tests and training.

Who can't join

  • Have internet access for less than 4 hours per week, whether at home, with family, at a public library, or elsewhere.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Enrolled in the Longitudinal Early-Onset AD Study (LEADS) parent study, and being classified via LEADS consensus criteria as having amyloid-positive Early Onset Alzheimer's Disease * Aged 40-64 years at the time of enrollment into LEADS * Fluent in English * In good general health and absent another neurological disorder * Have a knowledgeable informant. * Have had a Clinical Dementia Rating scale of 0.5 to 1.0 at the time of enrollment into LEADS * Have sufficient vision, hearing, comprehension, and manual dexterity to participate in the testing and training program Exclusion Criteria: • Have access to the internet (e.g., home, family, public library, etc.) for less than 4 hours per week

Study sites (1)

IN