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Speech Pattern Evaluation and Analysis for Knowledge of AD

Connected Language and Speech Along the Spectrum of ADRD: Digital Assessment and Monitoring

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
40 Years to 80 Years
Sex
All sexes
Healthy volunteers
Accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Time periods mentioned: 3 years
  • Procedures mentioned: Questionnaires

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "Participants will complete speech collection sessions and a survey at home using an iPad."
  • "Participants can expect to be in the study for 3 years."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study looks at whether changes in speech can measure thinking and memory in people at higher risk for Alzheimer's disease and related dementias. Participants will record speech and complete a survey at home on an iPad. The study lasts 3 years.

The goal of this observational study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer's disease and related dementias (ADRD). This study aims to clarify how speech may be affected by Alzheimer's disease. Participants will complete speech collection sessions and a survey at home using an iPad. Participants can expect to be in the study for 3 years.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Be enrolled in the Wisconsin Alzheimer's Disease Research Center (W-ADRC) Clinical Core or IMPACT studies, or the Wisconsin Registry for Alzheimer's Prevention (WRAP).
  • Have no thinking or memory problems, or have mild cognitive impairment (mild problems with thinking or memory).
  • Be 40–80 years old.
  • Have completed a W-ADRC or WRAP study visit in the past 12 months, or have one coming up within 12 months.
  • Have provided blood plasma (the liquid part of blood) to W-ADRC or WRAP. The listing's Alzheimer's-related requirement for this sample is incomplete.

Who can't join

  • Not currently enrolled in W-ADRC or WRAP.
  • Have dementia.
  • Be unable or unwilling to give consent to join the study.
  • Have a major condition affecting the brain or nerves.
  • Have a speech disorder.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Must be enrolled in the Wisconsin Alzheimer's Disease Research Center (W-ADRC) Clinical Core or IMPACT studies, or in the Wisconsin Registry for Alzheimer's Prevention (WRAP) * Cognitively unimpaired or have a diagnosis of Mild Cognitive Impairment (MCI) * Ages 40-80 years * Completion of a W-ADRC or WRAP study visit within the past or upcoming 12 months * Have provided W-ADRC or WRAP with blood plasma Alzheimer's Disease Exclusion Criteria: * Not actively enrolled in W-ADRC or WRAP * Diagnosis of dementia * Impaired capacity or unwilling to consent * Major neurological conditions * Speech disorders

Study sites (1)

WI