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Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Physiologic Effects of Nasal High Flow on Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD)

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years to 100 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests how high-flow air through the nose at 70 liters per minute affects walking during a 6-minute walk test. It also compares how short of breath people feel after walking with and without this airflow. It is for adults with COPD, a long-term lung disease that makes breathing hard.

This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Able to agree to join the study.
  • Age 18 or older.
  • Have COPD.
  • Able to walk without help.
  • Use no extra oxygen, or use oxygen through small nose tubes at 4 liters per minute or less.

Who can't join

  • Are pregnant.
  • Are on bed rest.
  • Cannot agree to join or cooperate with the study.
  • Use more than 4 liters per minute of extra oxygen, or need a breathing machine with a mask during the day.
  • Have a resting heart rate over 130 beats per minute, or a top blood pressure number of 90 or less or 180 or more.
  • Have metal implants in the chest area, such as a pacemaker, an implanted device that shocks the heart, plates, screws, rods, or replacement spinal discs.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Able to consent * Age 18 years or older * Diagnosis of COPD * Ability to ambulate without assistance * Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all Exclusion Criteria: * Pregnancy * Being on bedrest * Inability to consent or cooperate with the study * Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime * Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg) * Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)

Study sites (1)

FL