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Family Members at INcreased-risk for Developing Inflammatory Bowel Disease

Family Members at INcreased-risk for Developing Inflammatory Bowel Disease (FIND-IBD)

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
14 Years and older
Sex
All sexes
Healthy volunteers
Accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Procedures mentioned: Questionnaires, Blood draws

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "Participants will be asked once per year to complete a questionnaire and have their blood, stool, and urine collected."
  • "Parts of this study, such as the questionnaires and stool and urine collection, may be done from home, while other parts, such as the blood draw, will need to be done from Massachusetts General Hospital."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study follows people age 14 or older who do not have inflammatory bowel disease (IBD) but have a parent, sibling, or child with it. It looks at whether habits, diet, and signs in body samples can predict who gets IBD and whether it can be prevented. The study is expected to last about 10 years or longer, with yearly surveys and blood, stool, and urine samples; blood draws must be done at Massachusetts General Hospital.

First-degree relatives of people with inflammatory bowel disease ("IBD," including Crohn's disease and ulcerative colitis) have an increased risk for developing IBD themselves. This study will follow unaffected first-degree relatives (who do not have IBD) over time to understand if their behaviors, diet, and biomarkers for IBD can help predict who gets IBD and if IBD can be prevented in these high-risk individuals. Participants will be asked once per year to complete a questionnaire and have their blood, stool, and urine collected. The anticipated length of the study (registry) is approximately 10 years or longer. Parts of this study, such as the questionnaires and stool and urine collection, may be done from home, while other parts, such as the blood draw, will need to be done from Massachusetts General Hospital.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Be age 14 or older.
  • Be able to understand the study and agree to take part.
  • Be able to complete all study visits and tasks.
  • Be able to understand and complete the study surveys.
  • Have at least one parent, sibling, or child with IBD, a disease that causes swelling in the digestive tract. This includes Crohn’s disease, ulcerative colitis, or IBD with no clear type.

Who can't join

  • Already have a diagnosis of IBD.
  • Have signs or symptoms of IBD, as found during an interview with the study coordinator before joining.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Ability to give informed consent * Ability to complete all study visits and study-related procedures * Ability to understand and complete study questionnaires * Must have at least one first-degree relative with inflammatory bowel disease (Crohn's disease, ulcerative colitis, or IBD-unclassified) * Age ≥ 14 Exclusion Criteria: * Individuals with existing diagnoses of inflammatory bowel disease (ulcerative colitis, Crohn's disease, or IBD-unclassified) * Evidence of clinical signs or symptoms of IBD, which will be identified on pre-screening interview with the study coordinator.

Study sites (1)

MA