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Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection Registry Study

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years and older
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Procedures mentioned: Blood draws

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "Investigators will also take blood samples from participants to be used in future research."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study compares approved liver transplant methods for adults with colon or rectal cancer that has spread to the liver and cannot be removed by surgery. It looks at surgery results, hospital recovery, and survival one year after transplant. Researchers will also collect blood for future research.

Liver transplantation (LT) has become an accepted treatment for selected patients with unresectable liver metastases due to colorectal cancer (CRLM). The goal of this study is to look at and compare the clinical results of all the different approved methods (living vs. Deceased, whole organ vs. Split, one staged vs. Two staged) used to perform a standard liver transplant procedure for recipients with CRLM. Investigators will look at things like different procedure results, recovery in the hospital, and survival rates one year after the transplant. Investigators will also take blood samples from participants to be used in future research. All the transplant methods the investigators are comparing are standard practices approved by the United Network of Organ Sharing (UNOS).

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • You are 18 or older.
  • You are on the liver transplant list at Northwestern because colon or rectal cancer has spread to your liver.
  • You can give informed consent yourself, meaning you understand the study and agree to join without someone giving permission for you.

Who can't join

  • You cannot give informed consent yourself.
  • You are pregnant.
  • The lead study doctor decides that certain health, surgery, or body structure factors make you ineligible.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion: 1. All Patients of either gender ≥ 18 years of age who are listed for Liver transplant candidates at Northwestern with liver metastases due to colorectal cancer (CRLM). 2. Subjects must be able to provide informed consent themselves and without the use of a legally authorized representative (LAR), to be determined by the PI or Sub-I at the time of Consent. Exclusion: 1. Adults unable to consent 2. Pregnant Women 3. Certain clinical/surgical/anatomical parameters, at the discretion of the PI.

Study sites (1)

IL