Peanuts for Cardiometabolic, Brain, and Intestinal Health
Impact of Peanuts on Cardiometabolic, Cognitive, and Intestinal Health in Prediabetes Among Racially Diverse Populations
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 20 Years to 59 Years
- Sex
- All sexes
- Healthy volunteers
- Not accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
Not stated in the study description — ask the study team about visits and procedures.
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
In plain language
This 14-month study tests whether eating peanuts and peanut products each day improves heart, blood sugar, brain, and gut health. It is for adults ages 20–59 with prediabetes, or blood sugar that is higher than normal, from a range of racial backgrounds.
The overall objective of this 14-month randomized crossover study is to seek evidence demonstrating that daily consumption of peanuts and peanut products improve cardiometabolic, cognitive, and intestinal health in a racially diverse prediabetes population.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Who can join
- Men and women ages 20–59.
- Body mass index (BMI), a measure of weight compared with height, of 24.5–35.5.
- Prediabetes: fasting blood sugar of 100–125 mg/dL, HbA1c of 5.7–6.4%, or both. HbA1c measures average blood sugar over time.
- Able to give consent to join the study.
Who can't join
- Allergy to peanuts or peanut products.
- Use of insulin, other diabetes medicines, antibiotics, or medicines that reduce inflammation.
- Active cancer; gut, kidney, heart or blood vessel, thyroid, or nervous system disease; or a severe head injury.
- Smoking or drinking more than 2 alcoholic drinks per day.
- Use of antioxidant, probiotic, or prebiotic supplements, which protect cells or support gut bacteria.
- Pregnant or breastfeeding.
- Currently taking part in a weight loss program.
- For MRI scans: certain nervous system disorders, such as uncontrolled seizures; braces, a pacemaker, a hearing aid, or metal in the body or eyes. Metal may include pins, screws, shrapnel, plates, dentures, or certain tattoos containing metal.
Simplified for readability. The official criteria below are what the study team uses.
Official eligibility criteria
Inclusion Criteria: * men and women * 20-59 years of age * BMI: 24.5 - 35.5 kg/m\^2 * Prediabetes (fasting blood glucose levels 100-125 mg/dL and/or HbA1c between 5.7-6.4%) * Ability to give consent Exclusion Criteria: * Allergies to peanuts and peanut products * Use of insulin, antidiabetic, antibiotics, and anti-inflammatory drugs * Active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological diseases or severe head injury * Smoking * Consumes greater than 2 alcoholic beverages per day * Consumes antioxidant, probiotic, and prebiotic supplements * Pregnant or Lactating * Actively participating in a weight loss program MRI Exclusion Criteria: * Certain neurological disorders (e.g., uncontrolled seizure disorders) * Braces on their teeth, a cardiac pacemaker; hearing aid; other metal in the body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects
Study sites (1)
GA
- Georgia State University · Atlanta, GA 30303Rafaela G Feresin, PhD · Study contact · 404-413-1233 · peanuts@gsu.eduRafaela G Feresin, PhD · Principal investigatorTricia Z King, PhD · Sub-investigatorAndrew T Gewirtz, PhD · Sub-investigatorMore trials in Atlanta