RightFit
Not yet recruitingNot applicable

Preventing Early-Onset Colorectal Cancer in the VA

Preventing Early-Onset Colorectal Cancer in the VA Using a Multilevel Screening Intervention

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
45 Years to 49 Years
Sex
All sexes
Healthy volunteers
Accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests a way to help Veterans ages 45–49 get screened for colorectal cancer, which starts in the colon or rectum. It uses VA health records to find people at high risk and tells them and their care providers about that risk.

Colorectal cancer is a leading cause of cancer death among Veterans. The starting age for colorectal cancer screening has been lowered from 50 to 45 years in response to the rising incidence of early-onset colorectal cancer (EOCRC), but how to best engage younger Veterans in screening is unclear. The investigators will 1) develop and validate a novel risk score for EOCRC derived from the VA electronic health record data, 2) conduct a multilevel screening intervention that targets individuals aged 45-49 years and informs high-risk individuals and their providers about their risk status for EOCRC, and 3) determine barriers and facilitators to implementing the intervention using a qualitative process evaluation. Aim 2 is the focus of the trial. The overall goal of this study is to create and test a risk stratification approach to prevent EOCRC, which may be especially useful for younger individuals who are less likely to participate in preventive care.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • You are 45–49 years old when checked for the study.

Who can't join

  • You are up to date on colorectal cancer screening, such as a colonoscopy in the past 10 years or a FIT stool test in the past year.
  • You have had colorectal cancer.
  • You have had surgery to remove your whole colon.
  • You have a terminal illness, are in hospice care, or have a health record showing you are expected to live less than 6 months.
  • Your VA reminder for colorectal cancer screening and follow-up has been turned off because of your risk level or other health conditions.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Age 45-49 years at screening Exclusion Criteria: * Up-to-date with colorectal cancer (CRC) screening based on the USPSTF guideline (e.g., colonoscopy within the past 10 years or FIT within the past year) * Prior colorectal cancer (CRC) diagnosis * Prior total colectomy * Limited life expectancy (defined as terminal illness, hospice enrollment, or documented life expectancy \<6 months on the medical problem list or a health factor in the electronic health record (EHR) * Deactivated national colorectal cancer (CRC) screening and surveillance reminder (due to risk level or comorbidities)

Study sites (1)

NY