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Pollution Intervention to Impact Kids Asthma Study

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
8 Years to 17 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Visits mentioned: 3 visits
  • Time periods mentioned: 48 weeks

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "Participants will: * Receive standardized outdoor air pollution education and an asthma action plan * Provide nose and blood specimens * Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests whether adding air quality information to asthma care plans helps children ages 8–17 with asthma. It compares EPA and commercial Air Quality Index (AQI) information with a group that does not get added AQI information. It also looks at how genes work in the nose in children who report being more sensitive to outdoor air pollution.

The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are: * Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time? * Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution? Researchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma. Participants will: * Receive standardized outdoor air pollution education and an asthma action plan * Provide nose and blood specimens * Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Age 8–17 years.
  • A healthcare provider has diagnosed ongoing asthma, or occasional asthma with at least one severe attack in the past year. A severe attack means needing steroid medicine for at least 3 days, or an emergency room or urgent care visit requiring steroid medicine.
  • Have a smartphone or internet access at home.
  • Main home is in Allegheny County, Pennsylvania.
  • Only one person per household may join.
  • Have been checked for asthma by a healthcare provider in the past year.

Who can't join

  • Have another active, long-term lung disease, such as cystic fibrosis.
  • Have a disorder affecting nerves and muscles.
  • Have a long-term condition that limits walking without help.
  • Have cyanotic heart disease, a heart condition that causes low blood oxygen.
  • Plan to move out of Allegheny County, Pennsylvania, in the next 12 months.
  • Used steroid medicine in the nose, by mouth, by muscle shot, or through a vein within 4 weeks before being assigned to a study group.
  • Are currently in another study testing an asthma treatment or care approach.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * A healthcare provider diagnosis of persistent asthma (Steps 2-5 as defined by US guidelines) or intermittent asthma (Step 1) + at least one severe asthma exacerbation (defined by American Thoracic Society (ATS)/European Respiratory Society (ERS) criteria as requiring at least 3 days of systemic steroids or an Emergency Department/Urgent Care visit requiring systemic steroids) in the prior 12 months * Home access to a smartphone or internet * Primary residence in Allegheny County, PA * One participant per household * Age 8 -17 years * Healthcare provider evaluation for asthma in the prior year Exclusion Criteria: * Diagnosis of other active chronic respiratory diseases (e.g., cystic fibrosis, bronchopulmonary dysplasia, etc.) * Neuromuscular disorder * Chronic disorder limiting independent ambulation (e.g., spastic quadriplegia, etc.) * Cyanotic heart disease * Plans to relocate from Allegheny County, PA in the next year (12 months) * Use of intranasal or oral/intramuscular/intravenous corticosteroids 4 weeks prior to randomization * Current participation in another asthma intervention trial

Study sites (1)

PA