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The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
35 Years to 79 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study looks for biomarkers, or signs in the body, that may help find heart disease risk before symptoms start. It is for adults ages 40–79 with rheumatoid arthritis (RA) and at least one heart disease risk factor. The goal is to help start treatment earlier to prevent heart disease.

Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Have RA diagnosed by a rheumatologist, a doctor who treats joint and immune system diseases.
  • Are 40–79 years old.
  • Have at least one heart disease risk factor: prediabetes (blood sugar above normal), high blood pressure, a body mass index (BMI) over 30, or current or past cigarette smoking.

Who can't join

  • Take a statin, a medicine that lowers cholesterol, or cannot safely take one.
  • Take a cholesterol absorption inhibitor or a PCSK9 inhibitor, two types of cholesterol-lowering medicine.
  • Have diabetes.
  • Are pregnant.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * RA diagnosed by a rheumatologist * Age 40- 79 * ≥1 ASCVD risk factor including prediabetes, hypertension, BMI \>30, current or history of cigarette smoking Exclusion Criteria: * Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor * Patients with diabetes mellitus * Pregnancy

Study sites (3)

MA