RightFit
Not yet recruitingNot applicable

Effects of Whole Fruit on Blood Sugar in People With Type 2 Diabetes

Effects of Whole Fruit on Glycemic Control, Liver Fat, and Cardiovascular Disease Risk Factors in Adults With Type 2 Diabetes

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years and older
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Time periods mentioned: 17 weeks

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "The study will be a single-arm controlled feeding study to determine the effects of eating a large amount of whole fruit for 17 weeks on glycemic control (Aim 1), liver fat (Aim 2a), and cardiovascular disease risk factors (Aim 2b) in patients with insulin-independent type 2 diabetes."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

This study will determine the effects of consuming whole fruit on blood sugar control, liver fat, and cardiovascular health in adults with type 2 diabetes who are not treated with insulin.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Official eligibility criteria

Inclusion Criteria: * Aged ≥18 years * Diagnosed with type 2 diabetes * HbA1c between 6.5-12.0% * Fasting C-peptide level ≥0.5 ng/ml, indicating the patient does not have beta-cell failure, as measured at screening Exclusion Criteria: * On insulin * Evidence of latent autoimmune diabetes (LADA) or maturity-onset diabetes of the young (MODY) * Estimated glomerular filtration rate (eGFR) \<45 ml/min per 1.73 m² * Heart attack in the past 6 months or severe/unstable heart failure * On weight loss medication, including GLP-1 receptor agonists (e.g., semaglutide, dulaglutide) * Change in the dosage of a chronic medication that may affect study endpoints within the past 3 months * Clinically significant laboratory abnormality (e.g., abnormal hemoglobin levels) * Significant gastrointestinal disease, major gastrointestinal surgery, or gallstones * Significant cardiovascular, renal, cardiac, liver, lung, adrenal, or nervous system disease that might compromise participant safety or data validity * Evidence of cancer (other than non-melanoma skin cancer) within the last 5 years * Lost or gained more than 5 lbs (or more than 2% of body weight if the patient weighs \>250 lbs) of weight in the past 2 months * Pregnant, planning to become pregnant in the next 6 months, or breastfeeding * Major psychiatric condition that would affect the ability to participate in the study * Not able to eat the provided study meals (e.g., food allergies) * Behavioral factors or circumstances that may impede adherence to the dietary intervention * Not able to undergo the MRI scan (e.g., due to claustrophobia, implanted metal objects, or body girth ≥60 cm)

Study sites (1)

MA