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Low Versus High Load Training and Parkinson's Disease

Comparison of Changes in Neuromuscular and Functional Performance Due to Resistance Training With Low-Load or High-Load in Persons With Parkinson's Disease.

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
50 Years to 85 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study compares strength training with heavier loads to training with lighter loads in older adults with Parkinson's disease. It will test muscle strength, muscle power, and how well people do daily tasks.

This study will compare the effects of high-load resistance training to low-load resistance training, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Have Parkinson's disease at stages 1–3 on the Hoehn and Yahr scale, which rates how severe the disease is.
  • Can walk 50 meters without help.
  • Can understand and communicate in English.
  • Score above 18 on the Montreal Cognitive Assessment (MoCA), a test of memory and thinking.

Who can't join

  • Have an uncontrolled heart or blood vessel disease, or another nerve and muscle disease, that prevents exercise training.
  • Have a condition that causes inflammation throughout the body or makes the immune system attack the body, such as rheumatoid arthritis, or another serious illness.
  • Have an arm or leg injury that has not healed, or have not recovered from arm or leg surgery, and cannot do weight training.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Parkinson's Disease Hoehn \& Yahr Stages 1-3 * Able to walk 50m unassisted * Able to understand and communicate in English * A Montreal Cognitive Assessment (MoCA) score above 18 Exclusion Criteria: * Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program * Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness * Unresolved injury or surgery to the upper or lower limbs that prevents weight training.

Study sites (1)

FL