RightFit
Not yet recruitingPhase 1 / Phase 2

Sustained Release Oral Formulation For Treatment Of Parkinsons Disease

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years to 65 Years
Sex
All sexes
Healthy volunteers
Accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests a new way to slowly release two Parkinson’s medicines, LD and CD, from small pouches placed between the cheek and lower gum. The pouches release CD first, then LD, to help the body take in LD and keep it in the body longer. The study is for healthy adults ages 18 to 65.

LD/CD (medications to treat Parkinson's disease) will be delivered using an assembly of nested sachets made of permeable material. The assembly is placed in the oral/buccal cavity (between cheek and gum of lower jaw) and delivers continuous release of CD and LD for both transmucosal and gastrointestinal absorption. The combination of CD/LD in the inner sachet varies from that in the outer sachet. This allows for sequential release of CD and then LD to mimic a CD pretreatment method which is known to increase LD absorption and prolong its half-life.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Healthy men or women.
  • Age 18 to 65.
  • Willing and able to complete the study steps.

Who can't join

  • A health condition that requires taking medicine regularly.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Adult healthy male or female * Age 18 to 65 years * Willingness and ability to complete study procedures Exclusion Criteria: * medical conditions that require taking medications regularly.

Study sites (1)

MN