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Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
No age limits stated
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study looks at how exposure to the medicine hydroxyurea during pregnancy and breastfeeding affects women with sickle cell disease (SCD) and their babies. It uses past medical records to learn about pregnancy and breastfeeding outcomes.

The purpose of this research study is to document and understand the effects of hydroxyurea exposure for women with SCD and their babies, during both gestation and lactation.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Records from care before June 20, 2019 must be available.
  • Records must cover women with SCD who were exposed to hydroxyurea during pregnancy or while breastfeeding.
  • Women who lost a pregnancy, had a stillbirth, or gave birth at any stage of pregnancy are included.
  • Records must include pregnancy and breastfeeding outcomes for babies exposed to hydroxyurea and other babies born to the same women.

Who can't join

  • Medical records are not available, or information about hydroxyurea exposure is missing.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Medical records or data available from previous clinical care prior to June 20, 2019 of pregnant females with SCD, including women who miscarried, had a still birth, or completed labor at any gestational stage, with any hydroxyurea exposure during either pregnancy and/or while breastfeeding. * Medical records or data available from previous clinical care prior to June 20, 2019 about pregnancy and breastfeeding outcomes, both for babies with hydroxyurea exposure and other babies by these same women. Exclusion Criteria: * Unavailable medical records or lack of information about hydroxyurea exposure.

Study sites (1)

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