RightFit
RecruitingPhase 2 / Phase 3

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years and older
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major adverse kidney events in in patients with congestive heart failure undergoing cardiac catheterization and/or percutaneous coronary intervention.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Official eligibility criteria

Inclusion Criteria: * Age 18 years * Diagnosis of heart failure with reduced LVEF \<50% * Pre-procedure intravenous normal saline fluid restriction status * Society for Cardiovascular Angiography and Interventions (SCAI) AKI risk score (\>1%) * Referral for coronary angiogram and/or PCI * Suspected stable coronary artery disease or acute coronary syndrome Exclusion Criteria: * Inability to give informed consent * Unstable BP (SBP \> 200 or \<80 mmHg) at the time of enrolment * Upper limb peripheral arterial disease * Unavailability of at least one arm for RIPC/Sham-RIPC application * Kidney transplant * Renal disease requiring dialysis * Prior exposure to contrast media within 72hrs preceding coronary angiography * Pregnancy * Prisoner

Study sites (3)

PA

TX

VA