RecruitingPhase not listedNCT01757730
Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues
Sponsor: Arunark Kolipaka
Columbus, OH
Heart Failure clinical trials
336 recruiting studies in the US for heart failure, a condition in which the heart doesn't pump blood as well as it should.
Heart failure studies include Phase 3 medication trials and a large number of device, monitoring and care-transition studies, many enrolling during or soon after a hospital stay. Ejection fraction — how well the heart pumps — is a common eligibility cutoff, so it helps to know your most recent echocardiogram result. Kidney function is also checked often.
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By phase
Showing 40 of 336 studies
RecruitingPhase 3NCT07207811
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Sponsor: Novo Nordisk A/S
Phoenix, AZ · La Jolla, CA · Los Angeles, CA · +60 more sites
RecruitingEarly Phase 1NCT06507657
Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
Sponsor: University of Minnesota
Minneapolis, MN
RecruitingNot applicableNCT07205120
Fluid Guided Heart Failure Treatment at the Cleveland Clinic
Sponsor: Bodyport Inc.
Cleveland, OH
RecruitingNot applicableNCT07526896
Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing
Sponsor: Medtronic Cardiac Rhythm and Heart Failure
Minneapolis, MN
RecruitingPhase 3NCT03394365
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy
Sponsor: Pierre Fabre Medicament
Duarte, CA · La Jolla, CA · Loma Linda, CA · +37 more sites
RecruitingPhase not listedNCT07098858
The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
Sponsor: EBR Systems, Inc.
Mesa, AZ · Scottsdale, AZ · Jonesboro, AR · +9 more sites
RecruitingNot applicableNCT07574593
NORM-HF Pivotal Study
Sponsor: Foundry Innovation & Research 1, Limited (FIRE1)
Chula Vista, CA · Sacramento, CA · Jacksonville, FL · +22 more sites
RecruitingNot applicableNCT07644806
Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction
Sponsor: Old Dominion University
Norfolk, VA
RecruitingPhase 1NCT07830758
Resmetirom in Patients With MASH and HFpEF
Sponsor: Madrigal Pharmaceuticals, Inc.
Peoria, AZ · Oxnard, CA · Fort Myers, FL · +2 more sites
RecruitingPhase 3NCT07192952
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Sponsor: Bayer
Aurora, CO · Wilmington, DE · Gainesville, FL · +19 more sites
RecruitingPhase 4NCT07490067
Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score
Sponsor: University of Michigan
Ann Arbor, MI
RecruitingNot applicableNCT06222099
The HEARTFELT Study
Sponsor: Heartfelt Technologies
Little Rock, AR · Hackensack, NJ · Bala-Cynwyd, PA
RecruitingNot applicableNCT06364644
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
Sponsor: Johns Hopkins University
Baltimore, MD · Hagerstown, MD
RecruitingPhase 3NCT06424288
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Sponsor: Boehringer Ingelheim
Mobile, AL · Chula Vista, CA · +91 more sites
RecruitingPhase 2NCT06620523
Prevent Cardiac Surgery Associated AKI Trial
Sponsor: George Washington University
Washington D.C., DC
RecruitingPhase 3NCT06935370
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Sponsor: Boehringer Ingelheim
Beverly Hills, CA · Covina, CA · Encinitas, CA · +86 more sites
RecruitingNot applicableNCT02898181
Low Level Tragus Stimulation in Acute Decompensated Heart Failure
Sponsor: University of Oklahoma
Oklahoma City, OK
RecruitingNot applicableNCT06228209
Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer
Sponsor: Icahn School of Medicine at Mount Sinai
New York, NY
RecruitingPhase 3NCT06307652
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Sponsor: AstraZeneca
Alexander City, AL · Birmingham, AL · Fairhope, AL · +163 more sites
RecruitingPhase 3NCT06736574
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Sponsor: Cytokinetics
Alexander City, AL · Birmingham, AL · Tucson, AZ · +85 more sites
RecruitingNot applicableNCT06898515
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Sponsor: Reprieve Cardiovascular, Inc
Irvine, CA · Long Beach, CA · Sacramento, CA · +32 more sites
RecruitingNot applicableNCT06965504
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
Sponsor: Abiomed Inc.
Tampa, FL · Indianapolis, IN · Minneapolis, MN · +14 more sites
RecruitingPhase 4NCT07210606
Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment
Sponsor: VA Office of Research and Development
Detroit, MI
RecruitingPhase 2NCT07795814
A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
Sponsor: Edgewise Therapeutics, Inc.
Birmingham, AL · Little Rock, AR · Beverly Hills, CA · +25 more sites
RecruitingPhase not listedNCT04927429
Technical Development of Cardiovascular Magnetic Resonance Imaging
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Washington D.C., DC · Bethesda, MD
RecruitingPhase 1NCT07490054
Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure
Sponsor: Melana Yuzefpolskaya, MD
New York, NY
RecruitingNot applicableNCT05996328
CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
Sponsor: VA Office of Research and Development
Birmingham, AL · Little Rock, AR · Long Beach, CA · +18 more sites
RecruitingNot applicableNCT06291922
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation
Sponsor: University of Pennsylvania
Detroit, MI · Cleveland, OH · Philadelphia, PA · +1 more sites
RecruitingNot applicableNCT07400042
Peripheral Venous Pressure (PVP) Trial
Sponsor: Wake Forest University Health Sciences
Milwaukee, WI
RecruitingNot applicableNCT05427370
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Sponsor: Sunnybrook Health Sciences Centre
Los Angeles, CA · New Haven, CT · Louisville, KY · +3 more sites
RecruitingNot applicableNCT06670001
MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction
Sponsor: University of Pennsylvania
Philadelphia, PA
RecruitingNot applicableNCT06812533
Alleviant ALLAY-HFrEF Study
Sponsor: Alleviant Medical, Inc.
Los Angeles, CA · Sacramento, CA · +37 more sites
RecruitingNot applicableNCT07214376
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Sponsor: Pulnovo Medical, Inc.
Tucson, AZ · New Haven, CT · Weston, FL · +9 more sites
RecruitingPhase not listedNCT03581318
Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Bethesda, MD
RecruitingPhase 3NCT06929806
Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
Sponsor: Pharmacosmos A/S
Pasadena, CA
RecruitingPhase 2NCT06979362
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Sponsor: Novo Nordisk A/S
Birmingham, AL · Tucson, AZ · +26 more sites
RecruitingNot applicableNCT07069738
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Sponsor: Boston Scientific Corporation
Huntsville, AL · Mobile, AL · Phoenix, AZ · +39 more sites
RecruitingPhase not listedNCT07559903
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)
Sponsor: Emory University
Phoenix, AZ · Fort Lauderdale, FL · Atlanta, GA · +14 more sites
RecruitingNot applicableNCT03523416
Early Feasibility Study - Edwards APTURE Transcatheter Shunt System
Sponsor: Edwards Lifesciences
La Jolla, CA · Los Angeles, CA · San Francisco, CA · +16 more sites
Related conditions
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.