Sleep and Circadian Mechanisms in Hypertension
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 25 Years to 64 Years
- Sex
- All sexes
- Healthy volunteers
- Not accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
Not stated in the study description — ask the study team about visits and procedures.
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Official eligibility criteria
Inclusion Criteria: * Ages 25-64 * BMI 18.5-42kg/m2 * Hypertension (average resting blood pressure between 130/80 mmHg and 160/100 mmHg) Exclusion Criteria: * Over 5 pack-years of smoking; * Prior shift work within 12 months prior to the study; * Travel greater than three time zones for at least 3 months; * History of heart failure, cardiomyopathy, or history of bypass surgery, angioplasty, or previous myocardial infarction; * Acute or chronic diseases (except hypertension) that may affect outcome measures; * History of psychological conditions; * Sleep disorders, like severe sleep apnea, insomnia, etc.; * Prescription medications (Contraceptives and anti-hypertensive medications are permissible); * History of Illicit drug use and alcohol dependency; * 30 days free of cannabis use prior to the study; * Pregnancy; * Upper cut-off of 160/100 mmHg for BP
Study sites (1)
OR
- Oregon Health and Science University · Portland, OR 97239Saurabh S Thosar, PhD · Study contact · 503-494-2064 · clinphys@ohsu.eduSaurabh S Thosar, PhD · Principal investigatorMore trials in Portland