Hypertension clinical trials

397 recruiting studies in the US for hypertension, persistently high blood pressure.

Most high blood pressure studies here test care approaches — home monitoring, pharmacist or community programs, diet — rather than new drugs. Medication trials, including some Phase 4 studies of approved medicines, usually require blood pressure in a set range while on a stable treatment. Expect repeated blood pressure readings during screening.

Top locations

By phase

Showing 40 of 397 studies

RecruitingPhase 1NCT05206877

Topical Insulin for Glaucoma

Sponsor: Stanford University

Palo Alto, CA

RecruitingEarly Phase 1NCT06507657

Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

Sponsor: University of Minnesota

Minneapolis, MN

RecruitingPhase not listedNCT07174622

Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

Sponsor: Medtronic Vascular

Boston, MA

RecruitingPhase 2NCT01712620

Spironolactone for Pulmonary Arterial Hypertension

Sponsor: National Institutes of Health Clinical Center (CC)

Bethesda, MD

RecruitingPhase 2NCT03206060

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

Sponsor: National Cancer Institute (NCI)

Bethesda, MD

RecruitingPhase 2NCT05286814

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Sponsor: National Cancer Institute (NCI)

Bethesda, MD

RecruitingPhase not listedNCT06297291

Global Paradise System US Post Approval Study

Sponsor: ReCor Medical, Inc.

Long Beach, CA · Los Angeles, CA · Sacramento, CA · +43 more sites

RecruitingNot applicableNCT07238556

A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors

Sponsor: University of Connecticut

Farmington, CT · Hartford, CT · Storrs, CT

RecruitingPhase 4NCT05030545

Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

Sponsor: Brigham and Women's Hospital

Boston, MA

RecruitingPhase 2NCT05798923

LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Sponsor: IRulya Therapeutics Inc.

Tucson, AZ · New Haven, CT · Boston, MA · +1 more sites

RecruitingPhase not listedNCT06604650

Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study

Sponsor: Duke University

Miami, FL

RecruitingNot applicableNCT07005050

Renal Pelvic Denervation Pilot Trial

Sponsor: Verve Medical, Inc

Birmingham, AL · Surprise, AZ · Los Angeles, CA · +6 more sites

RecruitingPhase not listedNCT07132788

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass

Sponsor: University of Pennsylvania

Philadelphia, PA · Providence, RI

RecruitingPhase 3NCT07181109

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Sponsor: Alnylam Pharmaceuticals

Birmingham, AL · Fairhope, AL · +270 more sites

RecruitingPhase not listedNCT06265272

Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis

Sponsor: Massachusetts General Hospital

Charlestown, MA

RecruitingNot applicableNCT06854198

Glaucoma Screening to Enhance At-Risk Californians' Health

Sponsor: University of California, San Francisco

Fremont, CA · Oakland, CA · San Francisco, CA

RecruitingPhase 3NCT07285655

A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD

Sponsor: Liquidia Technologies, Inc.

Phoenix, AZ · Scottsdale, AZ · Los Angeles, CA · +10 more sites

RecruitingNot applicableNCT07842341

MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)

Sponsor: Texas Southern University

Houston, TX

RecruitingPhase not listedNCT03374215

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Bethesda, MD

RecruitingPhase 3NCT07179380

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Sponsor: Insmed Incorporated

Phoenix, AZ · Fresno, CA · Los Angeles, CA · +16 more sites

RecruitingPhase 3NCT07481981

A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)

Sponsor: Insmed Incorporated

Los Angeles, CA · Santa Barbara, CA · Torrance, CA · +8 more sites

RecruitingNot applicableNCT06685211

Electrical Stimulation for Vision Neuroenhancement in Glaucoma

Sponsor: Stanford University

Palo Alto, CA

RecruitingPhase 3NCT06822738

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Sponsor: AbbVie

Glendale, AZ · Culver City, CA · Petaluma, CA · +26 more sites

RecruitingNot applicableNCT06911632

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

Sponsor: Tempus AI

Birmingham, AL · Phoenix, AZ · +37 more sites

RecruitingPhase 2NCT07175038

A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)

Sponsor: AllRock Bio, Inc.

Phoenix, AZ · Rancho Cordova, CA · Aurora, CO · +8 more sites

RecruitingPhase 2NCT07553442

A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran

Sponsor: Alnylam Pharmaceuticals

Lake Forest, CA · Tampa, FL · Savannah, GA

RecruitingPhase 2NCT07783802

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

Sponsor: Eli Lilly and Company

Huntsville, AL · Tucson, AZ · +27 more sites

RecruitingNot applicableNCT07220876

Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

Sponsor: Avisi Technologies Inc.

Glendale, AZ · Los Angeles, CA · Petaluma, CA · +9 more sites

RecruitingNot applicableNCT06373289

Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

Sponsor: University of Alabama at Birmingham

Birmingham, AL · New Haven, CT

RecruitingNot applicableNCT07214376

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

Sponsor: Pulnovo Medical, Inc.

Tucson, AZ · New Haven, CT · Weston, FL · +9 more sites

RecruitingNot applicableNCT07540143

The REACH-OUT Trial

Sponsor: Northwestern University

Chicago, IL

RecruitingNot applicableNCT07783061

Reducing Cardiovascular Risks: The Role of Alcohol Use

Sponsor: The University of Texas at Arlington

Arlington, TX

RecruitingPhase not listedNCT07804277

Comparative Study of the Tomey FT-1000, and Goldmann Applanation Tonometer (GAT)

Sponsor: Tomey Corporation

Jacksonville, FL

RecruitingPhase 1NCT05967299

Study of Intravenous ZMA001 in Healthy Subjects

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Bethesda, MD

RecruitingPhase not listedNCT07390344

VIATORR® TIPS Study Evaluating 6-10mm Diameters (VIATIPS)

Sponsor: W.L.Gore & Associates

Atlanta, GA · Minneapolis, MN · Cleveland, OH

RecruitingPhase not listedNCT07780500

REFOCUS-HTN US-WEST: A Data Infrastructure to Characterize Individuals With Hypertension

Sponsor: Kaiser Permanente

Oakland, CA

RecruitingPhase not listedNCT01730092

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

Sponsor: National Institutes of Health Clinical Center (CC)

Bethesda, MD

RecruitingPhase 3NCT05470205

Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal

Sponsor: Thomas Jefferson University

Philadelphia, PA

RecruitingNot applicableNCT06059638

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

Sponsor: Orchestra BioMed, Inc

Scottsdale, AZ · Glendale, CA · Newport Beach, CA · +69 more sites

RecruitingPhase 2NCT07142356

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

Sponsor: Retension Pharmaceuticals. Inc.

Alexander City, AL · Birmingham, AL · Tucson, AZ · +31 more sites

Related conditions

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.