Immune Function and the Progression to T1D
Immune Function and the Progression to Type 1 Diabetes:
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 0 Years to 100 Years
- Sex
- All sexes
- Healthy volunteers
- Accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
Not stated in the study description — ask the study team about visits and procedures.
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Official eligibility criteria
Inclusion Criteria: able to have blood drawn - Exclusion Criteria: none \-
Study sites (3)
FL
- Kieran McGrail · Gainesville, FL 32610Kieran McGrail · Study contact · 352-273-9299 · mcgrail@pathology.ufl.eduTodd Brusko, PhD · Principal investigatorMore trials in Gainesville
OH
- The Ohio State University · Columbus, OH 43210Billur Akkaya, MD DPhil · Study contact · 614-688-1187 · billur.akkaya@osumc.eduMore trials in Columbus
TX
- Baylor College of Medicine, Center for Research Advancement - Texas Children's Hospital · Houston, TX 77030Maria Redondo, MD, PhD, MPH · Study contact · 832-822-1019 · redondo@bcm.eduFranca Erhiawarie · Study contact · 832-824-3372 · Franca.Ofudu@bcm.eduMore trials in Houston