Clinical trials in Columbus, OH

281 recruiting studies have a site in or near Columbus, OH, Ohio.

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Showing 40 of 281 studies

RecruitingPhase 3NCT07067463

A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

Sponsor: Zenas BioPharma (USA), LLC

Columbus, OH · +17 more sites

RecruitingPhase 1NCT07103018

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

Sponsor: K36 Therapeutics, Inc.

Columbus, OH · +12 more sites

RecruitingPhase 3NCT07213674

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

Sponsor: Amgen

Cincinnati, OH · Columbus, OH · Dayton, OH · +43 more sites

RecruitingPhase 3NCT07654374

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Columbus, OH · +73 more sites

RecruitingPhase 3NCT03150693

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Sponsor: Alliance for Clinical Trials in Oncology

Cincinnati, OH · Cleveland, OH · +452 more sites

RecruitingPhase 3NCT03394365

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Sponsor: Pierre Fabre Medicament

Cleveland, OH · Columbus, OH · +37 more sites

RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Akron, OH · Alliance, OH · Beavercreek, OH · +1147 more sites

RecruitingPhase 3NCT06498635

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Sponsor: National Cancer Institute (NCI)

Canton, OH · Centerville, OH · Columbus, OH · +278 more sites

RecruitingNot applicableNCT06891755

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

Sponsor: Apreo Health, Inc.

Cleveland, OH · Columbus, OH · +16 more sites

RecruitingPhase 4NCT06972056

Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

Sponsor: Mayo Clinic

Columbus, OH · +36 more sites

RecruitingPhase 2NCT07527650

Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus

Sponsor: Hanmi Pharmaceutical Company Limited

Columbus, OH · +19 more sites

RecruitingPhase 3NCT05980949

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Columbus, OH · Dayton, OH · Shaker Heights, OH · +145 more sites

RecruitingNot applicableNCT06423430

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Sponsor: Abbott Medical Devices

Cleveland, OH · Columbus, OH · +24 more sites

RecruitingPhase 1 / Phase 2NCT06810544

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Sponsor: Tango Therapeutics, Inc.

Columbus, OH · +14 more sites

RecruitingPhase 3NCT06819878

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Hoffmann-La Roche

Beavercreek, OH · Brunswick, OH · Cincinnati, OH · +92 more sites

RecruitingPhase 1NCT06846606

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

Sponsor: Auron Therapeutics, Inc.

Columbus, OH · +8 more sites

RecruitingPhase 2NCT07137598

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

Sponsor: Hoffmann-La Roche

Columbus, OH · +17 more sites

RecruitingPhase 3NCT07185009

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Sponsor: Sanofi

Columbus, OH · Westlake, OH · +35 more sites

RecruitingPhase 3NCT07391774

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Sponsor: National Cancer Institute (NCI)

Canton, OH · Centerville, OH · Columbus, OH · +200 more sites

RecruitingPhase 2NCT07610395

Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD

Sponsor: Altesa Biosciences, Inc.

Columbus, OH · Milford, OH · +35 more sites

RecruitingPhase 3NCT07674654

A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

Sponsor: Kallyope Inc.

Columbus, OH · Milford, OH · West Chester, OH · +110 more sites

RecruitingPhase not listedNCT07676565

Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study

Sponsor: Indiana University

Cincinnati, OH · Columbus, OH · +15 more sites

RecruitingPhase not listedNCT03019757

Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease

Sponsor: Douglas Scharre

Columbus, OH

RecruitingPhase 1NCT04301076

Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL)

Sponsor: National Cancer Institute (NCI)

Columbus, OH · +18 more sites

RecruitingPhase 1NCT06120283

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Sponsor: BeOne Medicines

Columbus, OH · +8 more sites

RecruitingPhase 3NCT07177352

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

Sponsor: Hoffmann-La Roche

Columbus, OH · +67 more sites

RecruitingPhase 3NCT07181109

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Sponsor: Alnylam Pharmaceuticals

Beavercreek, OH · Cincinnati, OH · +270 more sites

RecruitingPhase 3NCT07192952

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Sponsor: Bayer

Cincinnati, OH · Cleveland, OH · Columbus, OH · +19 more sites

RecruitingPhase not listedNCT07612878

The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry

Sponsor: Sanofi

Columbus, OH · +6 more sites

RecruitingPhase not listedNCT07875192

Hugo™ Robotic Assisted Surgery (RAS) System in Prostatectomy Patients Treated in an ASC Setting

Sponsor: Central Ohio Urology Group

Columbus, OH

RecruitingPhase 2NCT05691465

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

Sponsor: National Cancer Institute (NCI)

Columbus, OH · +12 more sites

RecruitingPhase 2NCT06317649

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Sponsor: National Cancer Institute (NCI)

Cleveland, OH · Columbus, OH · +223 more sites

RecruitingPhase 3NCT07064473

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Sponsor: Boehringer Ingelheim

Cincinnati, OH · Columbus, OH · +205 more sites

RecruitingPhase 2NCT07610473

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

Sponsor: Draig Therapeutics Ltd

Columbus, OH · +22 more sites

RecruitingPhase 3NCT07816367

A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine

Sponsor: Kallyope Inc.

Beachwood, OH · Blue Ash, OH · Cincinnati, OH · +69 more sites

RecruitingPhase not listedNCT02071134

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

Sponsor: Boston Scientific Corporation

Cleveland, OH · Columbus, OH · +27 more sites

RecruitingPhase 3NCT06307665

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

Sponsor: AstraZeneca

Cincinnati, OH · Columbus, OH · +117 more sites

RecruitingPhase 3NCT06312176

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Sponsor: Merck Sharp & Dohme LLC

Columbus, OH · +45 more sites

RecruitingNot applicableNCT06898515

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

Sponsor: Reprieve Cardiovascular, Inc

Cincinnati, OH · Cleveland, OH · Columbus, OH · +32 more sites

RecruitingPhase 3NCT06952504

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Sponsor: Merck Sharp & Dohme LLC

Centerville, OH · Cincinnati, OH · Columbus, OH · +50 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.