RightFit
RecruitingPhase not listed

Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume

Assessment of Pulmonary Blood Volume Using Contrast Echocardiography During Exercise

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years and older
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests whether a heart ultrasound with contrast during exercise can measure blood in the lungs as a stand-in for a pressure measurement taken with a tube inside the body. It is for people having a heart catheter test because they get short of breath during activity. Researchers will compare people with and without heart failure and lung blood vessel disease.

The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular disease.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • You are referred for a right heart catheter test during exercise to check why you get short of breath with activity. This test uses a thin tube to measure pressure inside the heart and lung blood vessels.
  • People with normal or reduced heart pumping strength may join, including those with different levels of high blood pressure in the lungs.

Who can't join

  • You cannot or do not want to have a heart ultrasound with contrast, a substance used to make the images clearer.
  • The study doctor thinks the ultrasound could make the results of your planned medical test less reliable.
  • You have had a bad reaction to heart ultrasound contrast before.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Patients referred to the cardiac catheterization laboratory for invasive exercise right heart catheterization for evaluating exertional dyspnea. Investigators will include patients with normal or low EF, and across the spectrum of pulmonary hypertension severity. Exclusion Criteria: * Patient inability or unwillingness to undergo echocardiography including a contrast method, or if echocardiography would, in the opinion of the investigator, somehow compromise the quality of data acquisition for the clinical case. * Prior adverse reaction to echo contrast administration

Study sites (1)

MN