Sleep Restriction and Parental History of Hypertension
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 18 Years to 35 Years
- Sex
- All sexes
- Healthy volunteers
- Accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
Not stated in the study description — ask the study team about visits and procedures.
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Official eligibility criteria
Inclusion Criteria * Healthy adults aged 18-35 years * Absence of any significant medical or psychiatric disease (as per the investigators' judgment) * Nonsmoker * Nonpregnant * History of normal sleep duration (reported average sleep duration between 7-9 hours/night and no habitual napping) * Hypertension status information available for both biological parents * Ability to understand study procedures and to comply with them for the entire length of the study * Ability to understand English and provide informed consent Exclusion Criteria * Age \<18 or \>35 years * Body mass index \<18.5 or ≥30 kg/m2 * Pregnant or lactating * Unable to determine history of HTN in participant's biological parents or subject being adopted * Use of tobacco, vaping, marijuana products or other drugs * Excessive caffeine consumption (\>400 mg/day) * Excessive alcohol consumption (\>7 drinks/week for women, \>14 drinks/week for men) * Office SBP/DBP ≥130/80 mmHg * Daytime ambulatory SBP/DBP ≥130/80 mmHg * Fasting glucose ≥126 mg/dl * Glomerular filtration rate \<60 mL/min/BSA * History of significant medical or psychiatric disorders (as per the investigators' judgment) * Regular use of prescription medications other than contraceptives * Use of melatonin supplements or any other over-the-counter sleep aid * Moderate-to-severe sleep disordered breathing (apnea/hypopnea index, AHI ≥15) or mild sleep disordered breathing (AHI 5-15) with daytime sleepiness (Epworth Sleepiness Scale \>10) * Moderate-to-severe insomnia (Insomnia Severity Index \>14) * Restless leg syndrome (as per the Cambridge-Hopkins questionnaire) * Excessive daytime sleepiness (Epworth Sleepiness Scale \>15) * Extreme chronotype (Morningness-Eveningness Questionnaire \>69 or \<31) * Night shift work * Ongoing participation in other research studies (as per the investigators' judgment) * Any other medical, geographic, or social factor making study participation impractical * Not English-speaking and/or inability to provide informed consent * Exclusionary for blood draws: hemoglobin \<11.6 g/dL in women / \<13.2 g/dL in men; participants with measured hemoglobin levels below these thresholds will be allowed to continue participate in study tests and procedures not involving blood draws.
Study sites (1)
MN
- Mayo Clinic in Rochester · Rochester, MN 55905Naima Covassin · Principal investigatorMore trials in Rochester