RightFit
RecruitingPhase 2

DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY

DANCE-BASED AVENUES TO ADVANCE NONPHARMACOLOGIC TREATMENT OF CHEMOTHERAPY EFFECTS (DAANCE): A MULTICENTER TRIAL

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
40 Years and older
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests Adapted Argentine Tango, a type of dance, for people with breast cancer who have nerve problems caused by chemotherapy. Researchers want to see if it helps movement control, eases symptoms, and helps people take part in treatment.

Up to 80% of breast cancer survivors experience chemotherapy-induced neuropathy that impairs quality of life and increases fall risk long into survivorship, yet treatment options for neuropathy remain limited. The successful treatment will target neurophysiologic mechanisms for restoring function while addressing patient-reported symptoms and participation in treatment. Toward this end, the investigators propose to study a noninvasive, social sensorimotor intervention - Adapted Argentine Tango - which targets motor control restoration, symptom alleviation, and treatment participation in concert.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Have stage I–IV breast cancer, including cancer that has spread to other parts of the body.
  • Finished taxane chemotherapy for breast cancer at least 3 months ago. There is no limit on how long ago.
  • Report symptoms of nerve problems caused by chemotherapy.
  • Have a balance test score that shows a possible risk of falling.
  • Can understand and follow directions for study tests and treatments.

Who can't join

  • Have an existing problem with the body's balance system.
  • Have poorly controlled diabetes, with an HbA1C blood sugar test result of 8 or higher.
  • Cannot walk. Walking aids and artificial limbs are allowed.
  • Have less than 10% hearing in both ears.
  • Your cancer doctor says another health problem makes the study activity unsafe, such as a slipped spinal disc or unstable cancer spots in bones.
  • Are currently in movement-based treatment, such as physical or occupational therapy. You may join after it ends if you still qualify.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Breast Cancer (BC) diagnosis of Stage I-IV including metastatic disease * completed taxane-based chemotherapy for BC at least 3 months ago (no limit on how long ago) * symptomatic for chemotherapy-induced neuropathy (self-report) * postural control score that indicates potential fall-risk * able to understand and comply with directions associated with testing and study treatments Exclusion Criteria: * pre-existing vestibular dysfunction * poorly controlled diabetes (hgA1C\>=8) * non-ambulatory (assistive and prosthetic devices allowed) * hearing impairment resulting in less than 10% hearing bilaterally * contraindication to participate in the experimental physical activity per the treating oncologist due to additional condition (e.g., herniated disc, unstable bone metastases) * currently in activity-based therapy (e.g., physical therapy, occupational therapy). May enroll if still meet eligibility criteria once activity-based therapy is complete.

Study sites (2)

CT

OH