Effects of Ultra Processed Food on Intestinal Energy Harvest
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 25 Years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
- Time periods mentioned: 2 weeks
- Procedures mentioned: Blood draws
Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.
Show the study's own words
- "This consists of one blood draw, one metabolic test which requires each person to remain awake in a small, enclosed room that measures oxygen and carbon dioxide consumption, and one body composition test."
- "Each person will be assigned to either 80% or 20% level of ultra processed food in the diet to start and will continue this diet for two weeks."
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
In plain language
This study compares two diets: one with 80% of calories from highly processed foods and one with 20%. Researchers will measure calories in stool (poop) to see how the diets affect how much energy the body takes in from food. The study is for otherwise healthy people with a BMI of 30–40 whose weight has stayed steady.
Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy. Some studies have shown that eating a diet high in ultra processed foods leads to weight gain, but these foods have not been studied enough to understand why. Recently, the gut microbiome has become a potential way to measure energy balance in the human body; this is done by measuring how many calories are in the stool. The investigators propose to test a very high ultra-processed food diet where 80% of calories are coming from ultra processed food and a low ultra processed food diet where 20% of the calories are coming from ultra processed food. This study will compare stool sample energy content of the two diets.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Who can join
- Have a body mass index (BMI) of 30–40. BMI is a measure based on height and weight.
- Have a weight that has stayed steady.
- Can download an app and are willing to use it throughout the study.
- Do your own grocery shopping.
- Are otherwise healthy.
Who can't join
- Are pregnant.
- Have had or plan to have weight-loss surgery.
- Have used medicines to treat obesity.
Simplified for readability. The official criteria below are what the study team uses.
Official eligibility criteria
Inclusion Criteria: * BMI 30-40kg/m2 * weight stable * able to download app and willing to use it for duration of study * does own grocery shopping * otherwise healthy Exclusion Criteria: * pregnancy * history of or planned bariatric surgery * history of anti obesity medications
Study sites (1)
NY
- Columbia University Irving Medical Center · New York, NY 10032Faris M Zuraikat, PhD · Study contactFaris M Zuraikat, PhD · Principal investigatorMore trials in New York