Breastmilk in Response to a Bout of Exercise
Breastmilk Composition in Response to a Bout of Exercise
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 18 Years to 45 Years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
Not stated in the study description — ask the study team about visits and procedures.
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
In plain language
This study looks at how one session of exercise after giving birth affects breastmilk. It aims to learn how these changes may help infant health. The study is for mothers who provide breastmilk.
The purpose of this study is to unveil the mechanistic benefits of a bout of postpartum maternal exercise on infant health that are provided by breastmilk.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Who can join
Who can't join
- Current disease in the arteries that supply the heart, or heart failure.
- For the inactive group: a planned exercise program at least 1 day a week. For the active group: a planned exercise program fewer than 3 days a week.
- A health problem the study doctor thinks could prevent you from finishing the study, such as abnormal liver or kidney tests, an injury, a muscle disorder, or cancer.
- Uncontrolled thyroid disease, or blood pressure above 160 for the top number or 90 for the bottom number at screening.
- Blood pressure, thyroid, depression, or cholesterol medicine that has not been stable for the past 2 months, or another medicine the study doctor thinks makes participation unsafe.
- Alcohol or recreational drug abuse, or tobacco smoking within the past 3 months.
- An infection that is not expected to clear before study procedures.
- Being pregnant.
Simplified for readability. The official criteria below are what the study team uses.
Official eligibility criteria
Exclusion Criteria: * Active coronary artery disease or heart failure. * Participation in a structured exercise program ≥ 1 day/week in the "inactive" subcohort or \< 3 days per week in the "active" subcohort. * A known medical condition that in the judgment of the investigator might interfere with the completion of the protocol such as the following examples: * Abnormal liver function test results (Transaminase \>2 times the upper limit of normal * Abnormal renal function test results (calculated GFR \<60 mL/min/1.73m2); * If on antihypertensive, thyroid, anti-depressant or lipid lowering medication, lack of stability on the medication for the past 2 months prior to enrollment in the study * Uncontrolled thyroid disease (TSH undetectable or \>10 mlU/L); testing required within three months prior to admission for subjects with a goiter, positive antibodies, or who are on thyroid hormone replacement, and within one year otherwise * Abuse of alcohol or recreational drugs * Active tobacco smoking within the past 3 months * Infectious process not anticipated to resolve prior to study procedures (e.g. meningitis, pneumonia, osteomyelitis). * Uncontrolled arterial hypertension (Resting diastolic blood pressure \>90 mmHg and/or systolic blood pressure \>160 mmHg) at the time of screening. * A recent injury to body or limb, muscular disorder, use of any medication, any carcinogenic disease, or other significant medical disorder if that injury, medication or disease in the judgment of the investigator will affect the completion of the protocol * Active pregnancy * Restrictions on Use of Other Drugs or Treatments: * Any other medication believed to be a contraindication to the subject's participation.
Study sites (1)
MN
- Mayo Clinic · Rochester, MN 55905Devanshi Gupta · Study contact · 507-255-6752 · Gupta.Devanshi@mayo.eduMark W Pataky, Ph. D., M.S. · Principal investigatorMore trials in Rochester