RightFit
RecruitingNot applicable

Stable Isotopes- Adults With Obesity

Assessing Metabolic Health With Stable Isotope Tracer Techniques in Adults With Obesity

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
19 Years to 59 Years
Sex
All sexes
Healthy volunteers
Accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Procedures mentioned: Biopsies, Questionnaires, Urine samples

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "Repeated blood, breath, urine, and muscle biopsies will be taken."
  • "Upon provision of informed consent, participants will receive an email with questionnaires designed to assess eligibility for the study through REDCap."
  • "Specifically, participants will be asked to complete a health and medical history questionnaire, physical activity readiness questionnaire (PARQ), International Physical Activity Questionnaire Long Form (IPAQ), and Godin-Shephard Leisure-Time Physical Activity Questionnaire (LTPAQ)."
  • "Information from the medical history questionnaire, PARQ, and LTPAQ will be used to assess exclusion criteria and the IPAQ be used to assess baseline habitual activity level."
  • "Upon completion of these questionnaires, the research team will review responses and determine eligibility."
  • "Urine samples: 30mL of urine at time points -30 min, 0 min, 240 min, 300 min, and 360 min."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests drinks with stable isotopes, which are forms of atoms used as tracers. It is for adults ages 19–59 with obesity who do little physical activity. All 8 participants will try two drink plans and give blood, breath, urine, and small muscle samples.

In a crossover design, 8 participants will receive caloric drinks containing stable isotopes. In one arm of the study, participants will consume 6 hourly drinks containing two stable isotopes. Repeated blood, breath, urine, and muscle biopsies will be taken. In the second arm, participants will consume 1 drink containing 75g glucose, labeled with two stable isotopes of glucose. Periodic blood and breath will be taken over three hours.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Are 19–59 years old.
  • Have a body mass index (BMI) of 30 or higher. BMI is a measure of weight compared with height.
  • Have a waist size of at least 102 cm for men or 88 cm for women.
  • Score below 14 on the Godin questionnaire, which asks about exercise during free time.

Who can't join

  • Are pregnant or become pregnant during the study.
  • Have any known food allergies.
  • Smoke.
  • Are physically active.
  • Have a known metabolic disease, which affects how the body uses food and energy.
  • Have lost or gained more than 10% of your body weight in the past 6 months.
  • Do not have regular menstrual periods or use hormonal birth control.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * ages 19-59 * Obese \>/= 30 kg/m\^2 and \>/= 102 cm for males and \>/= 88 cm for females * Godin Leisure-time or exercise questionnaire \<14 units Exclusion Criteria: 1. Pregnant or become pregnant 2. Any known food allergies 3. Smoker 4. Are physically active 5. Have any known metabolic diseases 6. Have been weight unstable within the last 6 months (lost or gained \>10% of body mass) 7. Non eumenorrheic or on a hormonal birth control

Study sites (1)

IL