RightFit
RecruitingPhase 1 / Phase 2

Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms

Virtual Remote Assessment of Transcranial Electrical Stimulation for Parkinson's Disease Motor Symptoms

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years to 80 Years
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Procedures mentioned: Phone or video check-ins

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "The entire study lasts 6 weeks and is conducted virtually through video calls and online assessments."
  • "Virtual onboarding includes supervised device setup and electrode placement training via video call."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study tests whether Sphere V3.0, a device that sends gentle electrical signals through small pads on the head, can ease shaking, stiffness, and slow movement in adults with Parkinson’s disease. Participants use it at home for 13 minutes each weekday for 3 weeks, then have 3 weeks of follow-up without treatment. The study uses video calls and online tests, and everyone gets the active treatment.

This study tests a new, non-invasive brain stimulation device called Sphere V3.0 to help improve movement problems in people with Parkinson's disease. The device delivers gentle electrical signals to the scalp using small electrodes placed on the head. Participants will use the device at home for 13 minutes each weekday (Monday through Friday) for 3 weeks, then be monitored for another 3 weeks without treatment. The entire study lasts 6 weeks and is conducted virtually through video calls and online assessments. The investigators will measure changes in Parkinson's symptoms using standard rating scales and video recordings of movement tasks like walking and hand tremor tests. Participants will also record videos of their movements at home using their smartphone or computer. The study includes 30 adults aged 18-80 who have been diagnosed with Parkinson's disease and have stable medication for at least 4 weeks. Participants must have reliable internet access and be able to follow the treatment schedule. The main goal is to see if this brain stimulation treatment can reduce motor symptoms like tremor, stiffness, and slowness of movement. The investigators will also check if any improvements last after treatment ends and monitor for any side effects. All participants receive the active device treatment - there is no placebo group. The device has been tested in over 250 people in previous studies with no serious adverse events reported

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Age 18–80 with a confirmed diagnosis of Parkinson’s disease.
  • Parkinson’s disease at stage 1–4 on the Hoehn & Yahr scale, which rates how much the disease affects movement.
  • Parkinson’s medicines have stayed the same for at least 4 weeks before joining.
  • Have reliable internet and can take part in video visits.
  • Can understand the study and agree to take part.
  • Willing to follow the treatment and follow-up schedule.

Who can't join

  • Metal implants in the head or neck, except dental fillings.
  • Pregnant or breastfeeding.
  • Severe skin problems where the pads would be placed.
  • History of epilepsy or seizures, unless this technology is specifically meant for that condition.
  • Stroke or a brain injury from trauma within the past 6 months.
  • Severe thinking or memory problems that prevent understanding treatment, or another nervous system disorder that makes this brain stimulation unsuitable.
  • Taking part in another clinical trial.
  • Unable to complete the full treatment and follow-up schedule.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * Adults 18-80 years with confirmed diagnosis of Parkinson's Disease * Hoehn \& Yahr stages 1-4 * Stable medication regimen for 4+ weeks prior to enrollment * Reliable internet access and telehealth capability * Ability to provide informed consent * Willingness to comply with treatment protocols and follow-up procedures Exclusion Criteria: * Metallic head/neck implants (excluding dental fillings) * Pregnancy or nursing status * Severe skin conditions at electrode placement sites * History of epilepsy or seizures (unless technology specifically indicated) * Recent stroke or traumatic brain injury (within 6 months) * Severe cognitive impairment preventing treatment understanding * Any neurological disorders contraindicating transcranial electrical stimulation * Current participation in other clinical trials * Inability to commit to full treatment and follow-up schedule

Study sites (1)

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