Clinical trials in Cleveland, OH

304 recruiting studies have a site in or near Cleveland, OH, Ohio.

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Showing 40 of 304 studies

RecruitingPhase 3NCT04047628

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Cincinnati, OH · Cleveland, OH · +21 more sites

RecruitingPhase 3NCT06136650

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Sponsor: Merck Sharp & Dohme LLC

Cleveland, OH · Gahanna, OH · Zanesville, OH · +60 more sites

RecruitingPhase 3NCT03150693

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Sponsor: Alliance for Clinical Trials in Oncology

Cincinnati, OH · Cleveland, OH · +452 more sites

RecruitingPhase 3NCT03394365

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Sponsor: Pierre Fabre Medicament

Cleveland, OH · Columbus, OH · +37 more sites

RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Akron, OH · Alliance, OH · Beavercreek, OH · +1147 more sites

RecruitingPhase 1 / Phase 2NCT06162221

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

Sponsor: Revolution Medicines, Inc.

Cleveland, OH · +28 more sites

RecruitingPhase 2NCT06317662

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Sponsor: National Cancer Institute (NCI)

Akron, OH · Cincinnati, OH · Cleveland, OH · +112 more sites

RecruitingNot applicableNCT06891755

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

Sponsor: Apreo Health, Inc.

Cleveland, OH · Columbus, OH · +16 more sites

RecruitingPhase 3NCT07071519

A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

Sponsor: AbbVie

Cleveland, OH · +11 more sites

RecruitingPhase 3NCT07611110

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

Sponsor: AstraZeneca

Cleveland, OH · Dayton, OH · +25 more sites

RecruitingPhase 2NCT05554393

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Sponsor: National Cancer Institute (NCI)

Cleveland, OH · +174 more sites

RecruitingPhase 1NCT06179069

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Cleveland, OH · +10 more sites

RecruitingNot applicableNCT06423430

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Sponsor: Abbott Medical Devices

Cleveland, OH · Columbus, OH · +24 more sites

RecruitingPhase 1NCT06465069

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

Sponsor: Eli Lilly and Company

Cleveland, OH · +22 more sites

RecruitingPhase 3NCT06819878

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Hoffmann-La Roche

Beavercreek, OH · Brunswick, OH · Cincinnati, OH · +92 more sites

RecruitingPhase 1NCT06879041

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

Sponsor: AstraZeneca

Cleveland, OH · +11 more sites

RecruitingPhase 1 / Phase 2NCT06973564

JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Cleveland, OH · +3 more sites

RecruitingPhase not listedNCT07098858

The WiSE®-UP Study (The WiSE System Utilization & Performance Study)

Sponsor: EBR Systems, Inc.

Cleveland, OH · +11 more sites

RecruitingPhase 3NCT06170788

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

Sponsor: Merck Sharp & Dohme LLC

Cleveland, OH · +14 more sites

RecruitingPhase 2 / Phase 3NCT06712316

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)

Sponsor: BioNTech SE

Canton, OH · Cincinnati, OH · +50 more sites

RecruitingPhase 4NCT07138560

BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease

Sponsor: The Cleveland Clinic

Cleveland, OH

RecruitingPhase 3NCT07192952

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Sponsor: Bayer

Cincinnati, OH · Cleveland, OH · Columbus, OH · +19 more sites

RecruitingPhase 2NCT06317649

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Sponsor: National Cancer Institute (NCI)

Cleveland, OH · Columbus, OH · +223 more sites

RecruitingPhase 3NCT06451757

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

Sponsor: Khondrion BV

Cleveland, OH · +2 more sites

RecruitingPhase 3NCT06671483

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines

Sponsor: Takeda

Cleveland, OH · Middleburg Heights, OH · +51 more sites

RecruitingPhase 3NCT06712355

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

Sponsor: BioNTech SE

Akron, OH · Canton, OH · Cincinnati, OH · +33 more sites

RecruitingPhase 3NCT06935370

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Sponsor: Boehringer Ingelheim

Cleveland, OH · Marion, OH · +87 more sites

RecruitingPhase 3NCT07028853

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Sponsor: Pfizer

Avon, OH · Cincinnati, OH · Cleveland, OH · +124 more sites

RecruitingPhase not listedNCT02071134

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

Sponsor: Boston Scientific Corporation

Cleveland, OH · Columbus, OH · +27 more sites

RecruitingPhase 1 / Phase 2NCT05786924

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Sponsor: Institut de Recherches Internationales Servier

Cleveland, OH · +20 more sites

RecruitingPhase 3NCT06023589

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

Sponsor: AstraZeneca

Cincinnati, OH · Cleveland, OH · Toledo, OH · +27 more sites

RecruitingNot applicableNCT06511141

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Sponsor: Axonics, Inc.

Cleveland, OH · +22 more sites

RecruitingPhase 3NCT06736574

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

Sponsor: Cytokinetics

Cincinnati, OH · Cleveland, OH · +85 more sites

RecruitingNot applicableNCT06898515

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

Sponsor: Reprieve Cardiovascular, Inc

Cincinnati, OH · Cleveland, OH · Columbus, OH · +32 more sites

RecruitingPhase 1NCT07094204

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Sponsor: Astellas Pharma Inc

Cleveland, OH · +10 more sites

RecruitingPhase 3NCT07144280

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Sponsor: Pfizer

Avon, OH · Cincinnati, OH · +238 more sites

RecruitingPhase 3NCT07225504

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

Sponsor: Novartis Pharmaceuticals

Cleveland, OH · +42 more sites

RecruitingPhase 1NCT07310420

A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer

Sponsor: TerSera Therapeutics LLC

Cleveland, OH · Columbus, OH · +24 more sites

RecruitingPhase 3NCT06405087

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Sponsor: Takeda

Cleveland, OH · +11 more sites

RecruitingPhase 3NCT06822738

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Sponsor: AbbVie

Cincinnati, OH · Cleveland, OH · +27 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.