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DSLT in Normal Tension Glaucoma (NTG) Asian Eyes

The Effectiveness of DSLT in Asian Normal Tension Glaucoma Patients

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
20 Years and older
Sex
All sexes
Healthy volunteers
Not accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

The goal of this clinical trial is to evaluate the efficacy of direct selective laser trabeculoplasty (DSLT) or laser treatment in Asian patients with normal tension glaucoma. The main question it aims to answer is: Does the DSLT reduce intraocular pressure (IOP) and medication use in Asian NTG subjects? Participants will attend routine follow-up visits with their eye surgeon and glaucoma testing such as optical coherence tomography (OCT) imaging and visual field test(s) after the laser study treatment.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Official eligibility criteria

Inclusion Criteria: * Asian descent * NTG diagnosis: glaucomatous optic neuropathy in patients with IOP measurements consistently lower than 21 mmHg * Mean deviation (MD) of the visual field between 0 to -12dB * No significant central vision loss within 5 degrees within 5th percentile * Age ≥20 years * NTG patients who are medically controlled on 1-3 medications and safe to wash out or IOP is still insufficient from medications and safe to washout * Shaffer grade II or more on 3 of the 4 quadrants * Central corneal thickness (CCT) 450-600µm * All participants are able to provide written informed consent before participation Exclusion Criteria: * Angle closure glaucoma or narrow angle status post laser peripheral iridotomy (LPI), or any other open angle glaucoma excluding NTG * History of SLT within last 2 years * History intraocular surgery including refractive surgery, except for history of cataract surgery that has been greater than 1 year * Patients anticipating cataract surgery during the study follow-up period * Unable to have DSLT procedure due to pre-limbal findings * Any presence of relevant ocular diseases including retinal disease with no confirmed cure

Study sites (1)

CA