Snacking Effects on the Brain Response to Foods and Satiety During Dieting
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 25 Years to 45 Years
- Sex
- All sexes
- Healthy volunteers
- Not accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
Not stated in the study description — ask the study team about visits and procedures.
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
This study plans to learn more about how different types of snacks may affect brain processes relating to eating behaviors during a diet intervention.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Official eligibility criteria
Inclusion Criteria: * 25-45 years old * BMI at least 27 kg/m2 * Comfortable completing a weight-loss intervention\\ * Willing to consume a daily snack of either walnuts or pretzels Exclusion Criteria: * Nut or wheat allergy * History of bariatric surgery * Current eating disorder * Current illicit substance use * Current pregnancy, lactation (or less than 3 months after stopping lactation), or less than 6 months postpartum * Uncontrolled hypertension (\>160/100 mmHg) * Significant endocrine/metabolic disease kidney disease, liver disease, or blood disease that would be anticipated to affect study results * Taking injectable medications, sulfonylureas, or meglitinides for diabetes treatment * Taking weight-loss medications, or steroids within \~3 months prior to study participation (e.g., GLP-1 receptor agonists) * Significant mental health changes within \~3 months prior to study participation (e.g., medication adjustments, new psychiatric diagnoses, hospitalization relating to mental health concerns) * Neurological illnesses or injury that would be anticipated to affect MRI data * Weight change greater than 10% within 3 months prior to study participation * Currently participating in another weight-loss study * Not comfortable eating the study-provided meals (with allowances for dietary preferences) and/or following a highly restrictive diet (e.g., vegan) * MRI-specific exclusion criteria (e.g., metal in the body, weight \>500 lbs
Study sites (1)
CO
- University of Colorado Anschutz Medical Campus · Aurora, CO 80045Kristina Legget, PhD · Study contact · 303-724-5809 · kristina.legget@cuanschutz.eduAllison Hild, BS · Study contact · 303-724-9024 · allison.hild@cuanschutz.eduKristina T Legget, PhD · Principal investigatorMore trials in Aurora