RightFit
RecruitingNot applicable

Postnatal Exercise to Activate Baby's Brown Fat

Impact of Acute Exercise and Habitual Physical Activity on Human Milk Composition and Childhood Obesity Risk

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years to 45 Years
Sex
Female only
Healthy volunteers
Accepted
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

Not stated in the study description — ask the study team about visits and procedures.

Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

In plain language

This study looks at how exercise during and after pregnancy may change breast milk. It also looks at how these changes may affect breastfed babies' energy use, growth, and risk of obesity. It is for people ages 18–45 with an uncomplicated pregnancy with one baby who plan to breastfeed only for more than 3 months.

The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk. Certain changes in breast milk after exercise may have an impact on how infants use energy. Understanding this process may improve public health recommendations for exercise during and after pregnancy. This study can help investigators learn more about how maternal exercise patterns may affect body growth and obesity risk in infants who are breastfed. This research may help identify how different factors can influence healthy weight and early development in infants.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Who can join

  • Age 18–45 when joining the study.
  • BMI of 18.5–40 before pregnancy or during the first 3 months. BMI is a measure of weight compared with height.
  • Pregnant with one baby, with no pregnancy complications.
  • Plan to feed the baby only breast milk for more than 3 months. If you have given birth more than once, you must have successfully breastfed a previous baby.
  • Give birth at 37 weeks to less than 42 weeks of pregnancy.
  • Baby's birth weight is above the 10th percentile for their week of pregnancy, meaning heavier than the smallest 10% of babies born at that stage.

Who can't join

  • A pregnancy-related medical reason that makes exercise unsafe at 1 month after birth.
  • Type 1 or type 2 diabetes that is not controlled, with HbA1c above 7%, or diabetes during pregnancy treated with insulin. HbA1c measures average blood sugar.
  • Baby did not grow as expected in the womb.
  • Pre-eclampsia, a pregnancy condition involving high blood pressure, or other pregnancy complications.
  • Use of alcohol, cannabis, or tobacco.
  • Baby has a known condition present at birth that affects how the body uses food or controls hormones, or another illness present at birth that affects feeding or growth.
  • Baby has major problems with body structure or development before birth.
  • Muscle, bone, or joint problems that would make exercise difficult.

Simplified for readability. The official criteria below are what the study team uses.

Official eligibility criteria

Inclusion Criteria: * 18-45 y of age at the time of enrollment * Pre-gravid or first trimester BMI 18.5 -40 kg/m2 * Uncomplicated singleton pregnancy * Intention to exclusively breastfeed for \>3 months and, if parity \>1, that they successfully breastfed a previous pregnancy * Term pregnancy (gestational age 37 to \<42 weeks) * Infant with birth weight \>10th percentile of weight for gestational age Exclusion Criteria: * Any obstetric contra-indication to exercise at 1 month * Diagnosis of uncontrolled (HbA1c \>7%) type 1 or type 2 diabetes, or gestational diabetes managed with insulin * Intrauterine growth restriction * Pre-eclampsia or other pregnancy complications * Alcohol, cannabis or tobacco use * Known congenital metabolic, endocrine disease, or congenital illness affecting infant feeding/growth * Major fetal anomalies * Musculoskeletal issues that would make exercise difficult

Study sites (2)

MA

OK