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Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity

Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity (REAL-BODY)

Who can join

As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.

Age
18 Years and older
Sex
All sexes
Healthy volunteers
Not stated
Compensation
Not stated

Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.

What to expect

No one can promise a trial will help you personally — that is what the research is trying to find out.

What participation involves

  • Procedures mentioned: Blood draws, MRI scans, X-rays

Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.

Show the study's own words
  • "The purpose of this study is to evaluate body composition across a variety of medical, professional, and commercial devices, including: bioelectrical impedance analysis (BIA) devices, 3-dimensional optical imaging (3DO), manual anthropometry measurements, dual-energy X-ray absorptiometry (DXA), magnetic resonance imaging (MRI), and blood tests."
  • "These include three-dimensional optical systems (3DO) housed in smartphones and multi-omics blood tests capable of estimating various body compartments."
  • "Currently, MRI is the gold standard method to measure visceral fat."
Compensation
Not stated
  • Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
  • Participants are monitored closely by the research team throughout the study.
  • Some participants may receive access to an investigational treatment, which is still being studied.
  • Your participation helps researchers learn whether this approach could help future patients.

About this study

The purpose of this study is to evaluate body composition across a variety of medical, professional, and commercial devices, including: bioelectrical impedance analysis (BIA) devices, 3-dimensional optical imaging (3DO), manual anthropometry measurements, dual-energy X-ray absorptiometry (DXA), magnetic resonance imaging (MRI), and blood tests. The secondary study purpose is to compare body composition measurements from BIA devices, 3DO, and manual anthropometry measurements within a 1-week period for a subset of the study population. The study plans to enroll 300 healthy (having no life-threatening conditions or diseases; male and female) participants, 18 years of age or older.

Compensation is read from the study's own description and may be missing — always confirm with the study team.

Eligibility

Official eligibility criteria

Inclusion Criteria: * Being willing to provide written informed consent prior to participation Being willing to complete the study visits and comply with the study procedures * Being willing to travel to the various study locations for On-site, DXA, MRI, and Phlebotomy visits * Being willing to change into appropriate form-fitting clothing for 3DO assessments and/or appropriate gowns for DXA and MRI imaging * Must have a BMI within the range of 18.5 - 45 kg/m2 * Being willing to refrain from all food, drink, and substances for 8 hours prior to the On-site visit(s) and phlebotomy visit * Being willing to refrain from all food, drink, and substances for 4 hours prior to the DXA and MRI scan visits * Being willing to refrain from any exercise or vigorous physical activity for 24 hours prior to all visits * Stable weight (no more than 5 kg change) for 3 months prior to screening * If recruited in the Phoenix, AZ area, participants must be willing to drive yourself to the Phoenix Office location for the On-site Visits 1 and 2 (if applicable) located at the Exponent Phoenix Office. Exclusion Criteria: * Being pregnant or attempting to become pregnant * Having medical implants, such as a pacemaker or metal joint replacements, or other metal implants contraindicated for MRI * Cosmetic implants, such as breast implants * Having a height greater than DXA scanning limit (77 inches) * Having a body weight greater than indicated for the equipment (400 lbs) * Prior amputation or major body-altering surgery that could invalidate body composition estimates * Having claustrophobia or a history of claustrophobia * Known HIV infection * Known Lipodystrophy * Known hydration abnormality (e.g., significant edema, end-stage renal disease, end-stage liver disease) * Severe illness or life-threatening conditions such as end-stage kidney, liver, lung disease, NYHA III-IV heart failure, or active malignancy

Study sites (3)

AZ

CA

MA