Precision Nutrition for Obesity and Prediabetes Prevention in Under-supported Communities
Building Capacity in Precision Nutrition to Address Obesity and Diabetes in Underserved Communities
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 18 Years to 65 Years
- Sex
- All sexes
- Healthy volunteers
- Not accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
- Procedures mentioned: Interviews
Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.
Show the study's own words
- "Qualitative interviews and focus group discussions will be used to explore participant experiences and intervention acceptability."
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
In plain language
This study tests whether a food plan tailored to each person and their culture improves weight and blood sugar more than standard nutrition advice. It is for African American and Hispanic/Latino adults in Texas who are overweight, have obesity, or have prediabetes.
This randomized controlled trial will evaluate the effectiveness of a culturally sensitive precision nutrition intervention for improving obesity- and diabetes-related outcomes among African American and Hispanic/Latino adults who are overweight, obese, or have prediabetes. Participants will be randomized to either a precision nutrition intervention group or a control group receiving standard nutrition counseling and educational materials. The intervention incorporates individualized dietary recommendations based on participant characteristics, including dietary habits, physical activity, socioeconomic factors, psychosocial factors, phenotype, and genotype. Outcomes will be assessed at baseline, 6 weeks, and 12 weeks and will include body weight, diet quality, fasting blood glucose, hemoglobin A1C, body composition, physical activity, blood pressure, and metabolic biomarkers. Feasibility, acceptability, and sustainability of the intervention will also be evaluated.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Who can join
- Are 18 to 65 years old.
- Are African American or Hispanic/Latino.
- Live in Texas.
- Have a BMI of 25 or higher, fasting blood sugar of 100–125 mg/dL, or both. BMI is a measure of weight compared with height. Fasting means not eating before the test.
- Have an A1C of 5.7%–6.4%. This blood test measures average blood sugar over the past few months.
- Have daily access to a cell phone and the internet.
- Can do physical activity at a moderate to hard effort.
- Can and will give informed consent, meaning you understand the study and agree to join.
Who can't join
- Do not meet all the requirements to join.
- Have followed a prescribed diet for any reason, including weight loss, in the past 3 months.
- Have been diagnosed with diabetes.
- Have heart or blood vessel disease.
- Have an eating disorder.
- Have lung, liver, or thyroid disease.
- Have Crohn’s disease, which causes swelling in the digestive tract.
- Are pregnant or breastfeeding.
Simplified for readability. The official criteria below are what the study team uses.
Official eligibility criteria
Inclusion Criteria: * Adults aged 18 to 65 years * African American or Hispanic/Latino adults * Residents of Texas * Body mass index (BMI) ≥ 25 kg/m² and/or fasting blood glucose levels of 100-125 mg/dL * Hemoglobin A1C (HbA1C) between 5.7% and 6.4% * Daily access to a cell phone and the internet * Able to participate in moderate-to-vigorous physical activity * Able and willing to provide informed consent Exclusion Criteria: * Do not meet the inclusion criteria * Following a prescribed diet for any reason, including weight loss, within the previous 3 months * Diagnosed diabetes mellitus * Cardiovascular disease * Eating disorders * Lung disease * Liver disease * Thyroid disease * Crohn's disease * Pregnant * Lactating
Study sites (1)
TX
- integrated Nutrition Intervention for Community and Health Enhancement Laboratory (iNICHE Lab) · Prairie View, TX 77446Janet Antwi, B.Pharm, M.S, Ph.D, RPh, RD, · Study contact · 9362612536 · jaantwi@pvamu.eduJanet Antwi, B.Pharm, M.S, Ph.D, RPh, RD, · Principal investigatorMore trials in Prairie View