Antihypertensive Self-titration in US Primary Care
Who can join
As published by the study on ClinicalTrials.gov. "Not stated" means the study hasn't said — ask the study team.
- Age
- 35 Years and older
- Sex
- All sexes
- Healthy volunteers
- Not accepted
- Compensation
- Not stated
Other requirements are listed under Eligibility below. Only the study team can confirm whether you can join.
What to expect
No one can promise a trial will help you personally — that is what the research is trying to find out.
What participation involves
- Time periods mentioned: 6 months
Only what the study's summary and detailed description on ClinicalTrials.gov say. Time periods may describe the whole study or a part of it — ask the study team what applies to you.
Show the study's own words
- "Participation in this study will last up to 6 months."
- Compensation
- Not stated
- Study-related exams and procedures are typically provided at no cost. This is how many trials work in general — confirm the details for this study with the study team.
- Participants are monitored closely by the research team throughout the study.
- Some participants may receive access to an investigational treatment, which is still being studied.
- Your participation helps researchers learn whether this approach could help future patients.
About this study
In plain language
This study tests a new way to manage high blood pressure at home for adults age 35 or older who take blood pressure medicine. Patients check their blood pressure and follow a plan made with their regular doctor to request medicine changes when needed. The study lasts up to 6 months.
The objective of this study is to pilot test self-titration intervention procedures. We are testing a new way to manage high blood pressure from home. In this study, patients will check their blood pressure at home and take steps to adjust their blood pressure medications if needed, following a plan outlined with a primary care doctor. Participation in this study will last up to 6 months. Participation will include a research visit to review the blood pressure management process. A primary care provider will also develop a medication plan for each participant to follow during the study and address any questions at their upcoming visit. During the study, each participant will be asked to check their blood pressure at home every day for 1-2 weeks a month using a study-provided blood pressure cuff. They will be asked to follow a set of instructions to request a medication change from their provider, based on their blood pressure readings. Participation may also include lab visits and additional visits with a primary care physician before making medication changes, if needed. There will also be a follow-up visit within 6 months.
Compensation is read from the study's own description and may be missing — always confirm with the study team.
Eligibility
Who can join
- You are age 35 or older.
- You are prescribed 1 or 2 medicines for high blood pressure.
- The average of your last 3 blood pressure readings from home and the clinic is above 130/80.
- You have an upcoming visit scheduled with your regular doctor.
- Your average blood pressure at a nurse visit is above 130/80.
Who can't join
- You cannot read English or Spanish.
- A nurse finds that you cannot check your own blood pressure.
- You have dementia or serious problems with memory or thinking, as judged by a nurse or your regular doctor.
- You are pregnant or trying to become pregnant.
- You have an illness expected to end your life or receive hospice care (care near the end of life).
- A family member is already in this study.
Simplified for readability. The official criteria below are what the study team uses.
Official eligibility criteria
Inclusion Criteria: * Age ≥35 years * Prescribed 1 or 2 antihypertensives * Average of last 3 BPs \> 130/80 (home \& clinic) * Upcoming scheduled PCP visit * Averaged BP \>130/80 at nurse visit Exclusion Criteria: * Unable to read English or Spanish * Unable to self-monitor (by nurse assessment) * Dementia or significant cognitive impairment (nurse / PCP discretion) * Pregnant or actively seeking to become pregnant * Terminal diagnosis or hospice * Family member already participating in the trial
Study sites (1)
MA
- Mass General Brigham · Somerville, MA 02150Julie C Lauffenburger, PharmD, PhD · Study contactMore trials in Somerville