RecruitingPhase 1 / Phase 2NCT07020221
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Sponsor: Verastem, Inc.
Boston, MA · +12 more sites
Colorectal Cancer clinical trials in Boston, MA
61 recruiting colorectal cancer studies with a site in Boston, MA.
RecruitingPhase 1 / Phase 2NCT05786924
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Sponsor: Institut de Recherches Internationales Servier
Boston, MA · +20 more sites
RecruitingNot applicableNCT05914766
An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer
Sponsor: Massachusetts General Hospital
Boston, MA
RecruitingPhase 2NCT07023289
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Sponsor: AbbVie
Boston, MA · +21 more sites
RecruitingPhase 3NCT07222800
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Sponsor: Pfizer
Boston, MA · Foxborough, MA · +251 more sites
RecruitingPhase 1 / Phase 2NCT05919264
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Sponsor: Parabilis Medicines, Inc.
Boston, MA · +29 more sites
RecruitingPhase 1NCT07114601
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Sponsor: Eli Lilly and Company
Boston, MA · +14 more sites
RecruitingPhase 1NCT04429542
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Sponsor: Bicara Therapeutics
Boston, MA · +14 more sites
RecruitingPhase 3NCT07228832
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Sponsor: Summit Therapeutics
Boston, MA · Danvers, MA · Newton, MA · +109 more sites
RecruitingPhase 1NCT07544589
A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers
Sponsor: Dispatch Biotherapeutics
Boston, MA · +6 more sites
RecruitingPhase 2NCT05673148
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
Sponsor: Alliance for Clinical Trials in Oncology
Boston, MA · +187 more sites
RecruitingPhase 2NCT06760819
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Sponsor: Bayer
Boston, MA · +10 more sites
RecruitingNot applicableNCT07059884
Distance-Based Exercise to Preserve Function and Prevent Disability
Sponsor: Alliance for Clinical Trials in Oncology
Boston, MA · +22 more sites
RecruitingPhase 1NCT05877599
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
Sponsor: AstraZeneca
Boston, MA · +18 more sites
RecruitingPhase 1NCT07578571
A Phase 1 Study of IM-1617 in Participants With Advanced Cancer
Sponsor: Immunome, Inc.
Boston, MA · +3 more sites
RecruitingPhase 1 / Phase 2NCT05482893
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
Sponsor: Phanes Therapeutics
Boston, MA · +10 more sites
RecruitingPhase 1NCT06218914
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
Sponsor: AstraZeneca
Boston, MA · +17 more sites
RecruitingPhase 1 / Phase 2NCT06047379
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Sponsor: Neonc Technologies, Inc.
Boston, MA · +7 more sites
RecruitingPhase 2NCT05489211
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Sponsor: AstraZeneca
Boston, MA · +16 more sites
RecruitingPhase 1 / Phase 2NCT06445062
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Sponsor: Revolution Medicines, Inc.
Boston, MA · +30 more sites
RecruitingPhase 1 / Phase 2NCT07629960
A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
Sponsor: Blueprint Medicines Corporation
Boston, MA · +9 more sites
RecruitingPhase not listedNCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Sponsor: Guardant Health, Inc.
Boston, MA · +32 more sites
RecruitingNot applicableNCT06202183
Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial
Sponsor: Dana-Farber Cancer Institute
Boston, MA
RecruitingNot applicableNCT04674267
Resilience and Equity in Aging, Cancer, and Health (REACH)
Sponsor: Dana-Farber Cancer Institute
Boston, MA
RecruitingPhase 2NCT04899908
Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
Sponsor: Brigham and Women's Hospital
Boston, MA
RecruitingPhase 1 / Phase 2NCT04851119
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Sponsor: Children's Oncology Group
Boston, MA · +20 more sites
RecruitingPhase 1NCT06586515
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
Sponsor: Eli Lilly and Company
Boston, MA · +23 more sites
RecruitingPhase 2NCT06792695
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
Sponsor: AstraZeneca
Boston, MA · +13 more sites
RecruitingPhase 1 / Phase 2NCT05592626
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Sponsor: Marengo Therapeutics, Inc.
Boston, MA · +12 more sites
RecruitingPhase 1 / Phase 2NCT03526835
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Sponsor: Merus B.V.
Boston, MA · +30 more sites
RecruitingPhase 1NCT06562192
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
Sponsor: Novartis Pharmaceuticals
Boston, MA · +8 more sites
RecruitingPhase 2NCT07527858
Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer
Sponsor: Gilead Sciences
Boston, MA · +4 more sites
RecruitingPhase 1NCT06179160
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Sponsor: Incyte Corporation
Boston, MA · +12 more sites
RecruitingPhase 1NCT07300150
A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors
Sponsor: PAQ Therapeutics, Inc.
Boston, MA · +4 more sites
RecruitingPhase not listedNCT07675967
Clonal Hematopoiesis Chemotherapy and Radiation Effects Study
Sponsor: Dana-Farber Cancer Institute
Boston, MA
RecruitingPhase 1 / Phase 2NCT06412198
A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations
Sponsor: M.D. Anderson Cancer Center
Boston, MA · +1 more sites
RecruitingPhase 1NCT06835569
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
Sponsor: Alterome Therapeutics, Inc.
Boston, MA · +10 more sites
RecruitingNot applicableNCT07220239
Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
Sponsor: Jessica D. St. Laurent, MD
Boston, MA
RecruitingPhase 1NCT06917079
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
Boston, MA · +15 more sites
RecruitingPhase 3NCT06950385
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Sponsor: Rapamycin Holdings Inc.
Boston, MA · +17 more sites
RecruitingPhase 1 / Phase 2NCT05379985
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Sponsor: Revolution Medicines, Inc.
Boston, MA · +20 more sites
RecruitingEarly Phase 1NCT02172651
Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases
Sponsor: Dana-Farber Cancer Institute
Boston, MA
RecruitingEarly Phase 1NCT07128355
Botensilimab, Balstilimab, and SBRT in Colorectal Cancer
Sponsor: Massachusetts General Hospital
Boston, MA
RecruitingPhase 1 / Phase 2NCT05692024
COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
Sponsor: Massachusetts General Hospital
Boston, MA
RecruitingNot applicableNCT07553572
Remote Monitoring and Symptom Management Digital Application
Sponsor: Patrick C. Johnson, MD
Boston, MA
RecruitingPhase 1NCT06723236
A Study of MGC028 in Participants With Advanced Solid Tumors
Sponsor: MacroGenics
Boston, MA · +5 more sites
RecruitingPhase 1NCT06720987
A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Sponsor: Kumquat Biosciences Inc.
Boston, MA · +10 more sites
RecruitingPhase 1 / Phase 2NCT06395519
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Sponsor: 858 Therapeutics, Inc.
Boston, MA · +13 more sites
RecruitingPhase 1 / Phase 2NCT06244771
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
Sponsor: Frontier Medicines Corporation
Boston, MA · +14 more sites
RecruitingPhase 4NCT04373564
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
Sponsor: Guerbet
Boston, MA · +13 more sites
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.