RightFit Trial Directory

Colorectal Cancer clinical trials in Durham, NC

23 recruiting colorectal cancer studies with a site in Durham, NC.

All trials in Durham, NC · All Colorectal Cancer trials

RecruitingPhase 3NCT07525206

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

Sponsor: AbbVie

Durham, NC · +17 more sites

RecruitingPhase 1 / Phase 2NCT05786924

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Sponsor: Institut de Recherches Internationales Servier

Durham, NC · +20 more sites

RecruitingPhase 2NCT07023289

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

Sponsor: AbbVie

Durham, NC · +21 more sites

RecruitingPhase 3NCT07222800

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Sponsor: Pfizer

Cary, NC · Durham, NC · +251 more sites

RecruitingPhase 1 / Phase 2NCT05919264

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Sponsor: Parabilis Medicines, Inc.

Durham, NC · +30 more sites

RecruitingPhase 1 / Phase 2NCT05482893

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

Sponsor: Phanes Therapeutics

Durham, NC · +10 more sites

RecruitingPhase 1NCT06004245

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

Sponsor: Vividion Therapeutics, Inc.

Durham, NC · +15 more sites

RecruitingPhase not listedNCT07124000

DESTINY-PANTUMOUR04

Sponsor: AstraZeneca

Durham, NC · Wilson, NC · +16 more sites

RecruitingPhase 3NCT05863195

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Sponsor: ECOG-ACRIN Cancer Research Group

Durham, NC · Raleigh, NC · Winston-Salem, NC · +59 more sites

RecruitingPhase 1 / Phase 2NCT06445062

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Sponsor: Revolution Medicines, Inc.

Durham, NC · +31 more sites

RecruitingPhase 1 / Phase 2NCT07488676

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

Sponsor: Astellas Pharma Global Development, Inc.

Durham, NC · +17 more sites

RecruitingPhase 1NCT07217171

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

Sponsor: EvolveImmune United, Inc

Durham, NC · +15 more sites

RecruitingPhase 1 / Phase 2NCT06638502

Safety of HRX215 in Patients After Minor and Major Liver Resection

Sponsor: HepaRegeniX GmbH

Durham, NC · +3 more sites

RecruitingPhase 3NCT06252649

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

Sponsor: Amgen

Durham, NC · Pinehurst, NC · +24 more sites

RecruitingPhase 1NCT06586515

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

Sponsor: Eli Lilly and Company

Durham, NC · +24 more sites

RecruitingPhase 1NCT05433142

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

Sponsor: Xencor, Inc.

Charlotte, NC · Durham, NC · +18 more sites

RecruitingPhase 2NCT06937177

Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy

Sponsor: Endevica Bio

Durham, NC · +24 more sites

RecruitingPhase 1NCT06835569

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

Sponsor: Alterome Therapeutics, Inc.

Durham, NC · +11 more sites

RecruitingPhase 1 / Phase 2NCT03947385

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

Sponsor: IDEAYA Biosciences

Durham, NC · +11 more sites

RecruitingNot applicableNCT06555588

Engage Psychosocial Intervention for Cancer Symptoms

Sponsor: Duke University

Durham, NC

RecruitingPhase 1NCT06778863

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Sponsor: Clasp Therapeutics, Inc.

Durham, NC · +20 more sites

RecruitingNot applicableNCT06371768

Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

Sponsor: Duke University

Durham, NC

Not yet recruitingPhase 1NCT07650357

A Study of CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101)

Sponsor: Clasp Therapeutics, Inc.

Durham, NC · +3 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.