RecruitingPhase 1 / Phase 2NCT07020221
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Sponsor: Verastem, Inc.
Philadelphia, PA · +12 more sites
Colorectal Cancer clinical trials in Philadelphia, PA
35 recruiting colorectal cancer studies with a site in Philadelphia, PA.
All trials in Philadelphia, PA · All Colorectal Cancer trials
RecruitingPhase 1NCT07594067
TCR1188-ABC Cells in KRAS-mutated Cancers
Sponsor: University of Pennsylvania
Philadelphia, PA
RecruitingPhase 2NCT07023289
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Sponsor: AbbVie
Philadelphia, PA · +21 more sites
RecruitingPhase 1 / Phase 2NCT05919264
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Sponsor: Parabilis Medicines, Inc.
Philadelphia, PA · Pittsburgh, PA · +29 more sites
RecruitingPhase 3NCT07228832
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Sponsor: Summit Therapeutics
Lebanon, PA · Philadelphia, PA · +109 more sites
RecruitingPhase 1NCT06218914
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
Sponsor: AstraZeneca
Philadelphia, PA · Pittsburgh, PA · +16 more sites
RecruitingPhase not listedNCT07124000
DESTINY-PANTUMOUR04
Sponsor: AstraZeneca
Philadelphia, PA · +17 more sites
RecruitingPhase 1NCT07277270
A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
Sponsor: GlaxoSmithKline
Philadelphia, PA · +4 more sites
RecruitingPhase 3NCT05863195
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
Sponsor: ECOG-ACRIN Cancer Research Group
Allentown, PA · Erie, PA · Jefferson Hills, PA · +59 more sites
RecruitingPhase 1 / Phase 2NCT06445062
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Sponsor: Revolution Medicines, Inc.
Philadelphia, PA · +31 more sites
RecruitingNot applicableNCT07638410
Prehabilitation in High-risk Oncologic Surgery
Sponsor: Fox Chase Cancer Center
Philadelphia, PA
RecruitingPhase 1NCT07217171
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
Sponsor: EvolveImmune United, Inc
Philadelphia, PA · +15 more sites
RecruitingPhase not listedNCT05059444
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Sponsor: Guardant Health, Inc.
Broomall, PA · Philadelphia, PA · York, PA · +30 more sites
RecruitingPhase 3NCT06252649
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Sponsor: Amgen
Philadelphia, PA · +25 more sites
RecruitingPhase 1NCT07216105
FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
Sponsor: Fate Therapeutics
Philadelphia, PA · +4 more sites
RecruitingPhase 1 / Phase 2NCT04851119
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Sponsor: Children's Oncology Group
Philadelphia, PA · Pittsburgh, PA · +19 more sites
RecruitingPhase 2NCT06792695
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
Sponsor: AstraZeneca
Philadelphia, PA · +13 more sites
RecruitingPhase not listedNCT06880055
Shield Post-Approval Study Protocol
Sponsor: Guardant Health, Inc.
Altoona, PA · Philadelphia, PA · Pottstown, PA · +66 more sites
RecruitingPhase 1 / Phase 2NCT04657068
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Sponsor: Artios Pharma Ltd
Philadelphia, PA · +39 more sites
RecruitingPhase 1 / Phase 2NCT03526835
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Sponsor: Merus B.V.
Philadelphia, PA · +30 more sites
RecruitingPhase 1NCT06179160
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Sponsor: Incyte Corporation
Philadelphia, PA · +12 more sites
RecruitingPhase 2NCT06948448
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
Sponsor: Ono Pharmaceutical Co., Ltd.
Philadelphia, PA · +10 more sites
RecruitingPhase 1NCT06756035
CT-95 in Advanced Cancers Associated With Mesothelin Expression
Sponsor: Context Therapeutics Inc.
Philadelphia, PA · +7 more sites
RecruitingPhase 1 / Phase 2NCT03947385
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
Sponsor: IDEAYA Biosciences
Philadelphia, PA · +11 more sites
RecruitingPhase 1 / Phase 2NCT05552755
Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)
Sponsor: Recursion Pharmaceuticals Inc.
Philadelphia, PA · +16 more sites
RecruitingPhase 1NCT06720987
A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Sponsor: Kumquat Biosciences Inc.
Philadelphia, PA · +10 more sites
RecruitingPhase 1 / Phase 2NCT06395519
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Sponsor: 858 Therapeutics, Inc.
Philadelphia, PA · +13 more sites
RecruitingPhase 1 / Phase 2NCT06244771
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
Sponsor: Frontier Medicines Corporation
Philadelphia, PA · +14 more sites
RecruitingPhase 1 / Phase 2NCT07030257
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
Sponsor: Tasca Therapeutics
Philadelphia, PA · +12 more sites
RecruitingNot applicableNCT07234968
Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy
Sponsor: Thomas Jefferson University
Philadelphia, PA
RecruitingPhase 1 / Phase 2NCT06055439
A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy
Sponsor: Chimeric Therapeutics
Philadelphia, PA · +3 more sites
RecruitingPhase 4NCT04373564
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
Sponsor: Guerbet
Hershey, PA · Philadelphia, PA · +14 more sites
RecruitingPhase 3NCT02000089
The Cancer of the Pancreas Screening-5 CAPS5)Study
Sponsor: Johns Hopkins University
Philadelphia, PA · Pittsburgh, PA · +7 more sites
RecruitingPhase 3NCT03659448
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
Sponsor: Surgimab
Philadelphia, PA · +5 more sites
Not yet recruitingPhase 1NCT07650357
A Study of CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101)
Sponsor: Clasp Therapeutics, Inc.
Philadelphia, PA · +3 more sites
Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.