Clinical trials in Philadelphia, PA

414 recruiting studies have a site in or near Philadelphia, PA, Pennsylvania.

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Showing 40 of 414 studies

RecruitingPhase 3NCT04047628

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Philadelphia, PA · +22 more sites

RecruitingPhase 3NCT06136650

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

Sponsor: Merck Sharp & Dohme LLC

Bala-Cynwyd, PA · Philadelphia, PA · +61 more sites

RecruitingPhase 1 / Phase 2NCT06546670

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

Sponsor: Novartis Pharmaceuticals

Philadelphia, PA · +8 more sites

RecruitingPhase 3NCT07654374

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics

Philadelphia, PA · +73 more sites

RecruitingPhase 3NCT03150693

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Sponsor: Alliance for Clinical Trials in Oncology

Allentown, PA · Bethlehem, PA · East Stroudsburg, PA · +452 more sites

RecruitingPhase 3NCT03394365

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Sponsor: Pierre Fabre Medicament

Philadelphia, PA · Pittsburgh, PA · +37 more sites

RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Allentown, PA · Altoona, PA · Beaver, PA · +1147 more sites

RecruitingPhase 2NCT06317662

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Sponsor: National Cancer Institute (NCI)

Allentown, PA · Danville, PA · Hershey, PA · +112 more sites

RecruitingPhase 3NCT06498635

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Sponsor: National Cancer Institute (NCI)

Allentown, PA · Bethlehem, PA · Bryn Mawr, PA · +278 more sites

RecruitingNot applicableNCT06891755

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

Sponsor: Apreo Health, Inc.

DuBois, PA · Philadelphia, PA · Pittsburgh, PA · +15 more sites

RecruitingPhase 4NCT06972056

Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study

Sponsor: Mayo Clinic

Philadelphia, PA · +36 more sites

RecruitingPhase 3NCT07071519

A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

Sponsor: AbbVie

Philadelphia, PA · Pittsburgh, PA · +10 more sites

RecruitingPhase 3NCT07190209

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

Sponsor: Sanofi

Philadelphia, PA · Pittsburgh, PA · +73 more sites

RecruitingPhase 4NCT07221877

A Study to Evaluate the Effect of KarXT on Urological Safety

Sponsor: Bristol-Myers Squibb

Philadelphia, PA · +15 more sites

RecruitingPhase 3NCT07404865

Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease

Sponsor: Vor Biopharma

Duncansville, PA · Philadelphia, PA · Willow Grove, PA · +44 more sites

RecruitingPhase 3NCT07513376

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

Sponsor: Merck Sharp & Dohme LLC

Philadelphia, PA · +23 more sites

RecruitingPhase not listedNCT04302272

STRIVE Post-Market Registry Study

Sponsor: Olympus Corporation of the Americas

Hershey, PA · Philadelphia, PA · +14 more sites

RecruitingPhase 1 / Phase 2NCT04959175

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Sponsor: National Cancer Institute (NCI)

Philadelphia, PA · +1 more sites

RecruitingNot applicableNCT06423430

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Sponsor: Abbott Medical Devices

Philadelphia, PA · +25 more sites

RecruitingPhase 1NCT06565195

A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease

Sponsor: Prevail Therapeutics

Philadelphia, PA · +6 more sites

RecruitingPhase 2NCT06731907

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Sponsor: Merck Sharp & Dohme LLC

Philadelphia, PA · +4 more sites

RecruitingPhase 1NCT06846606

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

Sponsor: Auron Therapeutics, Inc.

Philadelphia, PA · +8 more sites

RecruitingPhase 1 / Phase 2NCT07038343

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

Sponsor: Avenzo Therapeutics, Inc.

Philadelphia, PA · +18 more sites

RecruitingPhase 3NCT07391774

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Sponsor: National Cancer Institute (NCI)

Hershey, PA · Philadelphia, PA · +200 more sites

RecruitingNot applicableNCT07574593

NORM-HF Pivotal Study

Sponsor: Foundry Innovation & Research 1, Limited (FIRE1)

Philadelphia, PA · +23 more sites

RecruitingPhase 3NCT07674654

A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

Sponsor: Kallyope Inc.

Allentown, PA · Philadelphia, PA · Pittsburgh, PA · +110 more sites

RecruitingPhase 2NCT05798923

LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Sponsor: IRulya Therapeutics Inc.

Philadelphia, PA · +3 more sites

RecruitingPhase 3NCT06439082

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Sponsor: Novartis Pharmaceuticals

Easton, PA · Philadelphia, PA · +15 more sites

RecruitingPhase 1 / Phase 2NCT07020221

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

Sponsor: Verastem, Inc.

Philadelphia, PA · +12 more sites

RecruitingPhase not listedNCT07132788

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass

Sponsor: University of Pennsylvania

Philadelphia, PA · +1 more sites

RecruitingPhase 3NCT07181109

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Sponsor: Alnylam Pharmaceuticals

Camp Hill, PA · Danville, PA · Horsham, PA · +270 more sites

RecruitingPhase 3NCT07192952

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Sponsor: Bayer

Philadelphia, PA · Pittsburgh, PA · +20 more sites

RecruitingPhase 2NCT07459647

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

Sponsor: MapLight Therapeutics

Philadelphia, PA · +44 more sites

RecruitingPhase 2NCT06317649

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Sponsor: National Cancer Institute (NCI)

Allentown, PA · Danville, PA · Hershey, PA · +222 more sites

RecruitingPhase 3NCT07064473

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Sponsor: Boehringer Ingelheim

Beaver, PA · Camp Hill, PA · Philadelphia, PA · +205 more sites

RecruitingPhase 1NCT07594067

TCR1188-ABC Cells in KRAS-mutated Cancers

Sponsor: University of Pennsylvania

Philadelphia, PA

RecruitingPhase not listedNCT04997642

Parkinson's Disease and Movement Disorders Clinical Database

Sponsor: University of Pennsylvania

Philadelphia, PA

RecruitingPhase 3NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Sponsor: AstraZeneca

Abington, PA · Camp Hill, PA · Hershey, PA · +163 more sites

RecruitingPhase 3NCT06312176

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Sponsor: Merck Sharp & Dohme LLC

Philadelphia, PA · +45 more sites

RecruitingPhase 3NCT06430801

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Sponsor: Merck Sharp & Dohme LLC

Hershey, PA · Philadelphia, PA · Uniontown, PA · +84 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.