Clinical trials in Dayton, OH

54 recruiting studies have a site in or near Dayton, OH, Ohio.

Top conditions here

All conditions

Showing 40 of 54 studies

RecruitingPhase 3NCT04267848

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Sponsor: National Cancer Institute (NCI)

Akron, OH · Alliance, OH · Beavercreek, OH · +1147 more sites

RecruitingPhase 2NCT06317662

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Sponsor: National Cancer Institute (NCI)

Akron, OH · Cincinnati, OH · Cleveland, OH · +112 more sites

RecruitingPhase 3NCT06498635

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Sponsor: National Cancer Institute (NCI)

Canton, OH · Centerville, OH · Columbus, OH · +278 more sites

RecruitingPhase 3NCT07190209

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

Sponsor: Sanofi

Dayton, OH · +74 more sites

RecruitingPhase 3NCT05980949

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Columbus, OH · Dayton, OH · Shaker Heights, OH · +145 more sites

RecruitingPhase 3NCT07391774

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

Sponsor: National Cancer Institute (NCI)

Canton, OH · Centerville, OH · Columbus, OH · +200 more sites

RecruitingPhase 2 / Phase 3NCT06712316

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)

Sponsor: BioNTech SE

Canton, OH · Cincinnati, OH · +50 more sites

RecruitingPhase 3NCT07181109

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Sponsor: Alnylam Pharmaceuticals

Beavercreek, OH · Cincinnati, OH · +270 more sites

RecruitingPhase 4NCT06581328

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

Sponsor: Takeda

Cincinnati, OH · Dayton, OH · Liberty Township, OH · +98 more sites

RecruitingPhase 3NCT06307652

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Sponsor: AstraZeneca

Cincinnati, OH · Dayton, OH · +163 more sites

RecruitingPhase 3NCT06307665

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

Sponsor: AstraZeneca

Cincinnati, OH · Columbus, OH · +117 more sites

RecruitingPhase 3NCT07351045

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

Sponsor: Hoffmann-La Roche

Dayton, OH · +43 more sites

RecruitingPhase 3NCT07667803

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

Sponsor: AstraZeneca

Columbus, OH · Dayton, OH · +54 more sites

RecruitingPhase 2NCT06031688

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

Sponsor: SWOG Cancer Research Network

Canton, OH · Centerville, OH · Columbus, OH · +275 more sites

RecruitingPhase 2NCT06897475

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Sponsor: Eli Lilly and Company

Dayton, OH · +24 more sites

RecruitingPhase 2NCT07186101

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Sponsor: Eli Lilly and Company

Dayton, OH · +39 more sites

RecruitingPhase 3NCT05509777

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Sponsor: Eli Lilly and Company

Dayton, OH · +14 more sites

RecruitingPhase 2NCT06847321

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

Sponsor: Lighthouse Pharmaceuticals, Inc.

Dayton, OH · +38 more sites

RecruitingPhase 3NCT07359846

A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)

Sponsor: Generate Biomedicines

Dayton, OH · +20 more sites

RecruitingPhase 3NCT06976216

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Sponsor: Bristol-Myers Squibb

Columbus, OH · Dayton, OH · +26 more sites

RecruitingPhase 2NCT05673148

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

Sponsor: Alliance for Clinical Trials in Oncology

Centerville, OH · Cleveland, OH · +185 more sites

RecruitingPhase 3NCT05757102

A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

Sponsor: GlaxoSmithKline

Cincinnati, OH · Cleveland, OH · Dayton, OH · +25 more sites

RecruitingPhase 2NCT06887192

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

Sponsor: MapLight Therapeutics

Dayton, OH · Independence, OH · +35 more sites

RecruitingPhase 3NCT07253285

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

Sponsor: Novo Nordisk A/S

Columbus, OH · Dayton, OH · +32 more sites

RecruitingPhase 2NCT07845487

A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis

Sponsor: Palisade Bio

Brunswick, OH · Dayton, OH · Westlake, OH · +27 more sites

RecruitingPhase 3NCT07761117

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

Sponsor: AstraZeneca

Columbus, OH · Dayton, OH · +117 more sites

RecruitingPhase 3NCT05923073

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Janssen Research & Development, LLC

Dayton, OH · +13 more sites

RecruitingPhase 3NCT04743141

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

Sponsor: Pfizer

Cincinnati, OH · +112 more sites

RecruitingPhase 3NCT07184931

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Sponsor: Sanofi

Canton, OH · Cleveland, OH · Columbus, OH · +122 more sites

RecruitingPhase 3NCT06585787

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Cleveland, OH · Columbus, OH · Dayton, OH · +99 more sites

RecruitingPhase 3NCT07213674

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

Sponsor: Amgen

Cincinnati, OH · Columbus, OH · Dayton, OH · +42 more sites

RecruitingPhase 3NCT05877963

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

Sponsor: TG Therapeutics, Inc.

Cincinnati, OH · Cleveland, OH · Dayton, OH · +38 more sites

RecruitingPhase 3NCT04293562

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

Sponsor: Children's Oncology Group

Akron, OH · Cincinnati, OH · Cleveland, OH · +183 more sites

RecruitingPhase 3NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Sponsor: Ascletis Pharma (China) Co., Limited

Cincinnati, OH · Cleveland, OH · Columbus, OH · +81 more sites

RecruitingPhase 3NCT06677060

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Sponsor: AstraZeneca

Beavercreek, OH · Canton, OH · Cincinnati, OH · +195 more sites

RecruitingPhase 2NCT07415954

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Sponsor: Novo Nordisk A/S

Dayton, OH · +22 more sites

RecruitingPhase 3NCT05879926

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Sponsor: NRG Oncology

Akron, OH · Alliance, OH · +1223 more sites

RecruitingPhase 1 / Phase 2NCT04726241

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Sponsor: PedAL BCU, LLC

Akron, OH · Cincinnati, OH · Cleveland, OH · +161 more sites

RecruitingPhase not listedNCT05702645

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

Sponsor: Children's Oncology Group

Akron, OH · Cleveland, OH · +69 more sites

RecruitingPhase 3NCT07184996

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Sponsor: Sanofi

Canton, OH · Columbus, OH · +115 more sites

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.