Clinical trials in Lancaster, PA

22 recruiting studies have a site in or near Lancaster, PA, Pennsylvania.

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Showing 22 of 22 studies

RecruitingPhase 3NCT06345729

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Sponsor: Merck Sharp & Dohme LLC

Lancaster, PA · +14 more sites

RecruitingPhase 3NCT07028853

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Sponsor: Pfizer

Bala-Cynwyd, PA · Lancaster, PA · +125 more sites

RecruitingPhase 3NCT07174336

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Sponsor: Eli Lilly and Company

Bethlehem, PA · Lancaster, PA · Philadelphia, PA · +126 more sites

RecruitingPhase 2NCT07745361

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

Sponsor: Monte Rosa Therapeutics, Inc

Lancaster, PA · +13 more sites

RecruitingPhase 2NCT05673148

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

Sponsor: Alliance for Clinical Trials in Oncology

Chadds Ford, PA · Danville, PA · Hershey, PA · +185 more sites

RecruitingPhase 1 / Phase 2NCT06362252

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

Sponsor: Daiichi Sankyo

Lancaster, PA · Philadelphia, PA · +23 more sites

RecruitingPhase 3NCT07361510

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

Sponsor: Bristol-Myers Squibb

Lancaster, PA · Pittsburgh, PA · York, PA · +38 more sites

RecruitingNot applicableNCT06559891

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

Sponsor: SoniVie Inc.

Lancaster, PA · Philadelphia, PA · +32 more sites

RecruitingPhase 3NCT06561386

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Sponsor: Bristol-Myers Squibb

Lancaster, PA · Philadelphia, PA · +54 more sites

RecruitingPhase 3NCT07207811

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

Sponsor: Novo Nordisk A/S

Abington, PA · Allentown, PA · Hershey, PA · +60 more sites

RecruitingPhase 3NCT05879926

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Sponsor: NRG Oncology

Allentown, PA · Bethlehem, PA · +1223 more sites

RecruitingPhase not listedNCT00271180

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Sponsor: Medtronic

Allentown, PA · Bethlehem, PA · Danville, PA · +110 more sites

RecruitingPhase not listedNCT05489705

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Sponsor: Bristol-Myers Squibb

Bethlehem, PA · Lancaster, PA · Pittsburgh, PA · +57 more sites

RecruitingPhase 3NCT07567001

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Sponsor: Novo Nordisk A/S

Camp Hill, PA · Chambersburg, PA · Doylestown, PA · +203 more sites

RecruitingPhase 3NCT06748222

E-Mindfulness Approaches for Living After Breast Cancer

Sponsor: NRG Oncology

Carlisle, PA · Chambersburg, PA · Danville, PA · +378 more sites

RecruitingPhase 1NCT05071898

Pharmacogenetics of Response to GLP1R Agonists

Sponsor: University of Maryland, Baltimore

Lancaster, PA

RecruitingPhase 1NCT05413421

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

Sponsor: ORIC Pharmaceuticals

Bala-Cynwyd, PA · Lancaster, PA · +18 more sites

RecruitingNot applicableNCT03142152

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Sponsor: Cardiac Dimensions, Inc.

Danville, PA · Lancaster, PA · Mechanicsburg, PA · +72 more sites

RecruitingNot applicableNCT05650658

Left vs Left Randomized Clinical Trial

Sponsor: Baylor College of Medicine

Allentown, PA · Lancaster, PA · +54 more sites

RecruitingPhase 2NCT06134232

Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

Sponsor: Dendreon

Bala-Cynwyd, PA · Lancaster, PA · +29 more sites

RecruitingPhase not listedNCT06122077

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

Sponsor: Freenome Holdings Inc.

DuBois, PA · Lancaster, PA · Philadelphia, PA · +33 more sites

RecruitingNot applicableNCT06688396

Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)

Sponsor: Lancaster General Hospital

Lancaster, PA

Listings come from ClinicalTrials.gov and are provided for information only. Always confirm eligibility with the study team and talk with your doctor before making decisions about your care.